Type 2 diabetes trials in Czechia

In Czechia 24 Also abroad 1200

24 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Where
České Budějovice, Náchod, Plzeň 3, Prague, Prague 4, Praha 2
Age
18 years and over
People
2,000 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351045 · EU 2025-523104-71-00
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Where
Brandýs nad Labem, Jesenice, Prague, Prague 6, Praha, Praha 6
Age
18 years and over
People
1,600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351058 · EU 2025-523106-32-00
Phase 3Taking people
"AMBITION 2: A research study investigating how well zenagamtide lowers blood sugar and body weight compared to placebo in people with type 2 diabetes and chronic kidney disease treated with once daily basal insulin alone or in combination with metformin, SGLT2i, or both."
Where
Chrudim, Prague, Prague 4, Prague 9
Age
18 years and over
People
95 worldwide
Run by
Novo Nordisk A/S
See details and how to join2026-525471-13-00 · EU 2026-525471-13-00
Phase 3Taking people
AMBITION 3: A research study investigating how well zenagamtide at higher dose levels lowers blood sugar and body weight compared to semaglutide in people with type 2 diabetes treated with metformin, SGLT2i, or both
Where
Chrudim, Hranice I-Mesto, Olomouc, Prague, Prague 1, Praha 22
Age
18 years and over
People
595 worldwide
Run by
Novo Nordisk A/S
See details and how to join2026-525472-26-00 · EU 2026-525472-26-00
Phase 3Taking people
A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes
Where
Brandýs nad Labem, Brno-Stred, Lazce, Náchod, Ostrava, Prague
Age
18 years and over
People
600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07843485 · EU 2026-526189-25-00
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Where
Krnov, Ostrava, Prague 1, Praha 1
Age
18 years and over
People
1,035 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07282600 · EU 2025-523658-15-00
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Where
Holešov, Prague, Prague 8, Praha 4
Age
18 years and over
People
900 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07392190 · EU 2025-523659-73-00
Phase 3Not yet taking people in Czechia
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk
Where
Náchod, Nový Jičín, Prague, Roudnice Nad Labem, Usti Nad Labem
Age
45 years to 64 years
People
3,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07900633 · EU 2026-525919-14-00
Phase 3Taking people
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
Where
Hradec Králové, Humpolec, Jilove U Prahy, Moravska Ostrava A Privoz, Prague, Praha 6, Pribram VIII
Age
18 years and over
People
2,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662109 · EU 2025-523941-81-00
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Where
Benešov, Brno-Stred, Hodonín, Kladno, Moravska Ostrava A Privoz, Prague, Prague 10, Prague 14, Sedlcany, Steti, Votice
Age
18 years and over
People
2,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784725 · EU 2025-523379-41-00
Phase 3Taking people
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Where
Brandýs nad Labem, Brno-Královo Pole, Brno-Stred, Brno-Zidenice, Havířov, Prague, Uherské Hradiště, Znojmo
Age
18 years and over
People
11,800 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07064473 · EU 2025-521188-11-00
Phase 3Taking people
Efficacy and Safety of Once-Daily Oral ASC30 Compared with Placebo in Participants with Obesity or Overweight with Type 2 Diabetes Mellitus
Where
Pardubice, Praha 2, Praha 5, Uherské Hradiště
Age
18 years and over
People
549 worldwide
Run by
Ascletis Pharma (China) Co. Ltd.
See details and how to join2026-526336-39-00 · EU 2026-526336-39-00
Phase 3Taking people
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Brno-Stred, Dolní Břežany, Liberec, Náchod, Plzeň 3, Prague, Praha 22
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
Phase 3Taking people
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
Where
Pardubice, Prague, Uherské Hradiště
Age
18 years and over
People
1,560 worldwide
Run by
Ascletis Pharma (China) Co., Limited
See details and how to joinNCT07743450
Phase 3Taking people
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
Where
Brno, Broumov, Český Krumlov, Dolní Břežany, Hradec Králové, Náchod, Ostrava, Pardubice, Pilsen, Prague
Age
45 years and over
People
1,778 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07797335
No phaseTaking people
INNODIA Family & Friends Early-Stage T1D Detection Protocol
Where
Prague
Age
1 year to 45 years
People
30,000 worldwide
Run by
INNODIA iVZW
See details and how to joinNCT07118098
Phase 3Taking people
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin
Where
Broumov, Ceske Budejovice, Ostrava, Plzeň 3, Prague, Prague 4, Prague 8
Age
18 years and over
People
600 worldwide
Run by
AstraZeneca
See details and how to joinNCT07664553 · EU 2025-523935-20-00
No phaseTaking people
Bone Marrow Adipose Tissue in Relation to Bone and Energy Metabolism in Obesity and Type 2 Diabetes Mellitus
Where
Prague
Age
21 years to 55 years
People
45
Run by
General University Hospital, Prague
See details and how to joinNCT07731438
No phaseTaking people
Evaluate the Performance of the Dexcom G7 Continuous Glucose Monitoring (CGM) System in Critically Ill Patients Undergoing Major Abdominal Surgery and Solid Organ Transplantation Which Require Blood Glucose Monitoring for Intensive Insulin Therapy.
Where
Prague
Age
18 years and over
People
62
Run by
Institute for Clinical and Experimental Medicine
See details and how to joinNCT07611721
No phaseTaking people
Closed-loop in Adults With Type 2 Diabetes
Where
Prague
Age
18 years and over
People
224 worldwide
Run by
University of Cambridge
See details and how to joinNCT06579404
Phase 2Taking people
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
Where
Český Krumlov, Frýdek-Místek, Hodonín, Prague, Smiřice
Age
18 years and over
People
465 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06717698 · EU 2024-510846-15-00
No phaseTaking people
Global Research Initiative for Patients Screening on MASH
Where
Prague
Age
18 years to 75 years
People
10,000 worldwide
Run by
Julius Clinical
See details and how to joinNCT05651724
Phase 4Enrolling by invitation
Reducing Non-Alcoholic Steatohepatitis
Where
Prague 6
Age
18 years to 75 years
People
30
Run by
Military University Hospital, Prague
See details and how to joinNCT06519448 · EU 2024-518334-88-00
No phaseTaking people
Gastric Pathophysiology in Diabetes
Where
Ostrava, Prague
Age
18 years to 70 years
People
120 worldwide
Run by
Institute for Clinical and Experimental Medicine
See details and how to joinNCT06068114