Type 2 diabetes trials in Italy

In Italy 53 Also abroad 1247

35 of 53 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Where
Acquaviva delle Fonti, Ancona, Bergamo, Brescia, Catania, Catanzaro, Chieti, Cosenza, Ferrara, Florence, L'aquila, Milan, Monza, Naples, Palermo, Pavia, Pisa, Rivoli, Rome, Savona, Trieste, Turin, Varese
Age
18 years and over
People
11,800 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07064473 · EU 2025-521188-11-00
Phase 3Not yet taking people in Italy
AMBITION 3: A Research Study Investigating How Well Zenagamtide at Higher Dose Levels Lowers Blood Sugar and Body Weight Compared to Semaglutide in People With Type 2 Diabetes Treated With Metformin, SGLT2i, or Both
Where
Acquaviva delle Fonti, Bari, Florence, Milan, Parma, Perugia, Ravenna, Rome, Rozzano
Age
18 years and over
People
1,200 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07931573 · EU 2026-525472-26-00
Phase 3Active, not recruiting
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Where
Bari, Bergamo, Bologna, Catanzaro, Palermo, Perugia, Pisa, Rome, San Donato Milanese
Age
18 years and over
People
2,000 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351045 · EU 2025-523104-71-00
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Where
Bari, Bergamo, Bologna, Catanzaro, Milan, Palermo, Perugia, Rome
Age
18 years and over
People
1,600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351058 · EU 2025-523106-32-00
Phase 3Taking people
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Where
Bologna, Chieti Scalo, Palermo, Rome, Sesto San Giovanni
Age
18 years and over
People
954 worldwide
Run by
Pfizer
See details and how to joinNCT07595549 · EU 2026-525318-75-00
Phase 3Taking people
A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes
Where
Ancona, Florence, Genoa, Messina, Milan, Naples, Verona
Age
10 years to 17 years
People
170 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07668336 · EU 2025-524811-35-00
Phase 3Not yet taking people in Italy
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk
Where
Arezzo, Bologna, Chieti Scalo, Florence, Milan, Modena, Naples, Padova, Parma, Pisa, Rome, Rozzano, Siena, A.O.U. Policlinico Paolo Giaccone, Osepdale Civile Fr 5, ASL Città di Torino
Age
45 years to 64 years
People
3,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07900633 · EU 2026-525919-14-00
No phaseTaking people
Differentiating Heart Disease Between Adult-onset Autoimmune and Type 2 Diabetes
Where
Rome
Age
30 years and over
People
200
Run by
University of Roma La Sapienza
See details and how to joinNCT07911007
Phase 3Not yet taking people in Italy
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Where
Bologna, Milan, Palermo, Pisa, Rome, Rozzano, Sesto San Giovanni, Turin
Age
18 years and over
People
2,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784725 · EU 2025-523379-41-00
Phase 3Taking people
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
Where
Bari, Bologna, Chieti, Milan, Modena, Naples, Rome
Age
18 years and over
People
1,200 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662213 · EU 2025-523933-24-00
Phase 3Taking people
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
Where
Gussago, Messina, Milan, Pisa, Rome
Age
18 years to 64 years
People
220 worldwide
Run by
Khondrion BV
See details and how to joinNCT06451757 · EU 2025-522361-30-00
Phase 3Taking people
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Where
Bologna, Catania, Chieti, Florence, Latina, Milan, Pisa, Ravenna, Roma, San Donato
Age
18 years and over
People
4,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07667803
Phase 3Taking people
COLchicine and Non-enteric Coated Aspirin in the Cardiovascular Outcomes Trial of Patients With Type 2 Diabetes
Where
Acquaviva delle Fonti, Ancona, Bagno A Ripoli, Campobasso, Chieti Scalo, Ferrara, Florence, Foggia, Genoa, La Spezia, Milan, Pisa, Pistoia, Ravenna, Turin
Age
55 years to 80 years
People
10,000 worldwide
Run by
Montreal Heart Institute
See details and how to joinNCT05633810 · EU 2024-516646-19-00
Phase 3Active, not recruiting
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Ancona, Bologna, Brescia, Catanzaro, Genoa, Messina, Milan, Perugia, Pisa
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
No phaseTaking people
Development of Smart Food /Nutraceutical Solutions Dedicated to Cardiometabolic Disorders in Ageing
Where
Novara
Age
65 years and over
People
15
Run by
Azienda Ospedaliero Universitaria Maggiore della Carita
See details and how to joinNCT07817290
Phase 3Taking people
A trial to learn how safe elecoglipron is and how well it works in adults living with obesity or excess body weight with or without type 2 diabetes
Where
Bologna, Catania, Chieti, Florence, Latina, Milan, Pisa, Ravenna, Rome, San Donato Milanese
Age
18 years and over
People
1,010 worldwide
Run by
AstraZeneca AB
See details and how to join2025-524688-19-00
Phase 3Not yet taking people in Italy
Study of a DPP 4 inhibitor and an SGLT2 inhibitor used together compared with each treatment alone in adults with type 2 diabetes treated with metformin.
Where
Ascoli Piceno, Catanzaro, Milan, Parma, Rome, Verona
Age
18 years and over
People
760 worldwide
Run by
Tecnimede-Sociedade Tecnico-Medicinal S.A.
See details and how to join2025-524606-15-00
No phaseTaking people
EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Patients
Where
Milan
Age
18 years and over
People
105
Run by
Fondazione Don Carlo Gnocchi ETS
See details and how to joinNCT05987410
Phase 3Taking people
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Where
Milan
Age
18 years to 65 years
People
57 worldwide
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT04786262 · EU 2024-513929-23-00
Phase 3Not yet taking people in Italy
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
Where
Catanzaro, Chiavari, Chieti, Lucca, Milan, Naples, Ravenna, Roma
Age
45 years and over
People
1,778 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07797335
No phaseTaking people
Connected Care for Type 2 Diabetes Self-Management
Where
Ancona, Ascoli Piceno, Civitanova Marche, Fabriano, Fano, Fermo, Iesi, Pesaro, Province of Macerata, San Benedetto del Tronto
Age
18 years and over
People
388
Run by
Marche Region Regional Health Agency
See details and how to joinNCT07149610
Phase 4Not yet taking people in Italy
A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels Compared to Daily Basal Insulins in Adults With Type 2 Diabetes
Where
Bari, Catanzaro, Chieti Scalo, Fermo, Florence, Messina, Milan, Naples, Palermo, Perugia, Ravenna, Rome
Age
18 years and over
People
586 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07112339 · EU 2024-520068-32-00
No phaseTaking people
Normast3 for Adults With Diabetic Polyneuropathy
Where
Rome
Age
18 years to 80 years
People
40
Run by
University of Roma La Sapienza
See details and how to joinNCT07689214
No phaseTaking people
Pocket-X Gel Non-surgical Periodontal Therapy
Where
Verona
Age
18 years to 80 years
People
70
Run by
Universita di Verona
See details and how to joinNCT07372677
No phaseTaking people
Interdisciplinary Counselling in DIAbetes
Where
Perugia
Age
25 years to 80 years
People
123
Run by
Centro Universitario Ricerca Interdipartimentale Attivita' Motoria
See details and how to joinNCT07583355