Type 2 diabetes trials in South Africa

In South Africa 7 Also abroad 1200

7 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
Where
Brackenfell, Cape Town, Claremont, Durban, eMkhomazi, Johannesburg, KwaDukuza, Paarl, Pretoria
Age
18 years and over
People
2,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662109 · EU 2025-523941-81-00
Phase 3Taking people
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Where
Benoni, Bloemfontein, Cape Town, Centurion, Century City, Durban, Gauteng, Johannesburg, Pietermaritzburg, Pretoria, Raslouw, Somerset West, Soweto, Tygervalley, Worcester, Wynberg
Age
18 years and over
People
11,800 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07064473 · EU 2025-521188-11-00
Phase 3Taking people
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Where
Bellville, Bloemfontein, Cape Town, Chatsworth, Claremont, Durban, eMkhomazi, Johannesburg, Midrand, Wentworth
Age
18 years and over
People
4,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07667803
Phase 3Taking people
A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting
Where
Bloemfontein, Cape Town, East London, eMkhomazi, Johannesburg, Kimberley, Krugersdorp, Lenasia, Paarl, Pretoria, Somerset West
Age
18 years to 65 years
People
130 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07613307
Phase 3Taking people
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Bloemfontein, Cape Town, Durban, Johannesburg, Lenasia, Mossel Bay, Paarl, Cape Town, Port Elizabeth, Pretoria, Somerset West
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
No phaseTaking people
iCaReMe Global Registry: Multinational Real-world Evidence in Cardiorenal and Metabolic Diseases
Where
Florida, Parow, Umhlanga
Age
18 years and over
People
35,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT03549754
Phase 3Taking people
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus
Where
Brackenfell, Cape Town, Claremont, Durban, eMkhomazi, Johannesburg, KwaDukuza, Paarl, Pretoria
Age
18 years and over
People
800 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662044 · EU 2025-523936-37-00