Ulcerative colitis: open trials in Canada

45 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT07577856
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Barrie GI Associates, Barrie · South Edmonton Gastroenterology Research Clinic, Edmonton · Gastroenterology and Internal Medicine Research Institute (GIRI), Edmonton · Charlton Digestive Disease Centre, Hamilton · Viable Clinical Research, Kentville · London Digestive Disease Institute, London · Clinique IMD, Montreal · CHUM - Centre hospitalier universitaire de Montreal, Montreal · Toronto Immune and Digestive Health Institute Inc, Toronto · GI Research Institute (G.I.R.I.), Vancouver
Registry updated 2026-11-03
NCT06619990
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Trial Treatment · Phase 1/2 · Xencor, Inc.
Xencor Investigative Site, London · Xencor Investigative Site, Montreal · Xencor Investigative Site, Scarborough · Xencor Investigative Site, Vancouver
Registry updated 2026-10-30
NCT06979336
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Trial Treatment · Phase 2 · Genentech, Inc.
London Digestive Disease Institute, London · Hopital Maisonneuve-Rosemont d/b/a CIUSSS de l'Est-de-l'le-de-Montral, Montreal · Clinique IMD, Montreal
Registry updated 2026-10-27
NCT07012395
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Trial Treatment · Phase 2 · Spyre Therapeutics, Inc.
Site 082, Chicoutimi · Site 085, Greater Sudbury · Site 086, London · Site 083, London · Site 087, Montreal · Site 081, Montreal · Site 084, Toronto
Registry updated 2026-10-27
NCT07071519
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
Trial Treatment · Phase 3 · AbbVie
Alberta Children's Hospital /ID# 272635, Calgary · University of Alberta Hospital /ID# 271168, Edmonton · London Health Sciences Centre - Verspeeten Family Cancer Centre /ID# 271157, London
Registry updated 2026-10-27
NCT07697456
Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
Trial Treatment · Phase 2 · AbbVie
Diex Recherche Quebec Inc. /ID# 282307, Québec
Registry updated 2026-10-27
NCT07470879
A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis
Trial Treatment · Phase 2 · Pfizer
University of Alberta, Edmonton · CHU de Quebec-Universite Laval, Québec · Children's Hospital Research Institute of Manitoba, Winnipeg · Health Sciences Centre Winnipeg, Winnipeg
Registry updated 2026-10-26
NCT07184996
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Sanofi
Charlton Digestive Disease Centre - Site Number : 1240009, Hamilton · Oakville Endoscopy Center Inc. DBA ABP Research Services Corp. - Site Number : 1240010, Oakville · Toronto Immune and Digestive Health Institute Inc. (TIDHI) - Site Number : 1240003, Toronto
Registry updated 2026-10-23
NCT07463183
A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Prairie Institute of Liver and Luminal Advanced Research ( Site 1008), Lethbridge · Centre Hospitalier de l Universite de Montreal - CHUM ( Site 1001), Montreal · Toronto Western Hospital ( Site 1006), Toronto
Registry updated 2026-10-23
NCT07483073
A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease
Trial Treatment · Phase 2 · Eli Lilly and Company
Prairie Institute of Liver and Luminal Advanced Research Ltd (PILLAR), Lethbridge · London Digestive Disease Institute, London · Tdda Inc., Vaughan
Registry updated 2026-10-22
NCT07845487
A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 2 · Palisade Bio
Site CA-005, Calgary · Site CA-004, Edmonton · Site CA-006, Greater Sudbury · Site CA-003, London · Site CA-007, Montreal · Site CA-001, Montreal · Site CA-002, Scarborough Village
Registry updated 2026-10-21
NCT05076175
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb
Local Institution - 0083, Hamilton · Local Institution - 0104, Toronto · The Hospital for Sick Children, Toronto
Registry updated 2026-10-20
NCT07185009
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Sanofi
Investigational Site Number :1240004, Edmonton · Investigational Site Number : 1240009, Hamilton · Investigational Site Number : 1240013, London · Investigational Site Number : 1240006, New Westminster · Investigational Site Number : 1240003, Toronto
Registry updated 2026-10-16
NCT02308917
The Canadian Children Inflammatory Bowel Disease Network (CIDsCaNN)
Research · The Hospital for Sick Children
Alberta Children's Hospital, Calgary · Stollery Children'S Hospital, Edmonton · Izaak Walton Killam Hospital (Iwk), Halifax · Hamilton Health Sciences, Hamilton · CHILDRENS HOSPITAL OF WESTERN ONTARIO, Lawson Health Research Institute, London · Hôpital Ste-Justine, Montreal · Montreal Children's Hospital, Montreal · Children's Hospital of Eastern Ontario (CHEO), Ottawa · Janeway Children'S Health & Rehabilitation Centre, St. John's · SickKids Hospital, Toronto · Children'S Hospital of Bc, Vancouver · Winnipeg Children'S Hospital, Winnipeg
Registry updated 2026-10-09
NCT06042387
Genome Analysis Across Populations in Inflammatory Bowel Disease
Research · Mount Sinai Hospital, Canada
Sinai Health System, Toronto
Registry updated 2026-10-09
NCT07341282
Investigation of Vancomycin Efficacy in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis
Trial Treatment · Phase 2 · McMaster University
McMaster Children's Hospital - Digestive Diseases Clinic, Hamilton
Registry updated 2026-10-09
NCT07186101
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Trial Treatment · Phase 2 · Eli Lilly and Company
Charlton Digestive Disease Centre, Hamilton · London Digestive Disease Institute, London · London Health Sciences Centre, London · West Gta Research Inc., Mississauga · C.I.C. Mauricie inc., Trois-Rivières
Registry updated 2026-10-08
NCT07415044
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 2 · Eli Lilly and Company
Health Sciences North, Greater Sudbury · QEII Health Sciences Centre, Victoria General Site, Halifax · London Digestive Disease Institute, London
Registry updated 2026-10-08
NCT04844606
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Trial Treatment · Phase 3 · Eli Lilly and Company
London Health Sciences Centre, London · The Hospital for Sick Children, Toronto
Registry updated 2026-10-07
NCT06937086
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Trial Treatment · Phase 3 · Eli Lilly and Company
London Digestive Disease Institute, London · London Health Sciences Centre, London · Clinique IMD, Montreal · The Ottawa Hospital - General Campus, Ottawa · (G.I.R.I.) GI Research Institute Foundation, Vancouver · Vancouver General Hospital, Vancouver
Registry updated 2026-10-07
NCT07158242
A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Hoffmann-La Roche
Hospital for Sick Children, Toronto
Registry updated 2026-10-06
NCT03816345
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Trial Treatment · Phase 1 · National Cancer Institute (NCI)
University Health Network, Princess Margaret Hospital, Toronto
Registry updated 2026-10-05
NCT06548399
Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease
Research · McMaster University
McMaster University, Hamilton
Registry updated 2026-10-01
NCT07013578
TIDHI Mental Health in IBD Patients Study
Trial Treatment · TIDHI Innovation Inc.
Toronto Immune and Digestive Health Institute, North YORK
Registry updated 2026-09-29
NCT07814274
Prospective Intestinal Ultrasound Study for Artificial Intelligence Algorithm Development
Research · University of British Columbia
IBD Centre of BC, Vancouver
Registry updated 2026-09-10

All Ulcerative colitis trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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