Ulcerative colitis trials in Czechia

In Czechia 20 Also abroad 381

20 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
An Adaptive, Dose-Ranging, Phase 2 Study of Eltrekibart Given Alone or in Combination with Mirikizumab for the Treatment of Adult Patients with Moderately to Severely Active Ulcerative Colitis
Where
Brno-Sever, Brno-Zidenice, Slaný, Zlin
Age
18 years and over
People
587 worldwide
Run by
Eli Lilly & Co.
See details and how to join2023-507853-13-00 · EU 2023-507853-13-00
Phase 3Taking people
Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
Where
Brno-Zidenice, Hradec Králové
Age
18 years and over
People
1,380 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06651281 · EU 2024-513533-20-00
Phase 2Enrolling by invitation
Long-term Safety and Efficacy of Multiple Long-acting Antibodies Alone and in Combinations for IBD
Where
Brno, Brno-Sever, Brno-Zidenice, Klatovy IV, Moravska Ostrava A Privoz, Pardubice, Prague
Age
18 years and over
People
645 worldwide
Run by
Spyre Therapeutics, Inc.
See details and how to joinNCT07652294 · EU 2025-524640-35-00
Phase 3Taking people
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Where
Brno, Hradec Králové, Ostrava, Prague, Ústí nad Labem
Age
18 years to 70 years
People
350 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06937086 · EU 2024-520209-38-00
Phase 2Taking people
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Where
Hradec Králové, Pardubice, Prague, Slaný, Sternberk, Uherské Hradiště, Vsetín
Age
18 years to 80 years
People
1,431 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07415044
Phase 3Taking people
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
Where
Brno-Sever, České Budějovice, Hradec Králové, Kladno, Ostrava, Prague
Age
18 years and over
People
644 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07577856 · EU 2026-525923-26-00
Phase 2Taking people
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Where
Olomouc
Age
18 years and over
People
224 worldwide
Run by
Genentech, Inc.
See details and how to joinNCT06979336 · EU 2025-520690-39-00
Phase 2Taking people
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Where
Brno, Brno-Sever, Brno-Zidenice, Klatovy IV, Moravska Ostrava A Privoz, Pardubice, Prague
Age
18 years to 75 years
People
645 worldwide
Run by
Spyre Therapeutics, Inc.
See details and how to joinNCT07012395 · EU 2025-521242-26-00
Phase 3Taking people
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Where
Brno, Hradec Králové
Age
16 years to 80 years
People
980 worldwide
Run by
Sanofi
See details and how to joinNCT07184996
Phase 2Taking people
A study of LY4268989 in participants with Moderately to Severely Active Ulcerative Colitis (EMERALD-3)
Where
Hradec Králové, Pardubice, Prague, Prague 4, Slaný, Sternberk, Uherské Hradiště, Vsetin
Age
18 years and over
People
104 worldwide
Run by
Eli Lilly & Co.
See details and how to join2025-524404-29-00 · EU 2025-524404-29-00
Phase 2Taking people
Confirmatory Clinical Study in Active Ulcerative Colitis
Where
Brno-Zidenice, Hradec Králové, Prague, Slaný
Age
16 years and over
People
204 worldwide
Run by
MRM Health NV
See details and how to joinNCT07296315 · EU 2025-524682-24-00
Phase 2Taking people
A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis
Where
Brno, Havířov, Hradec Králové, Prague, Slaný
Age
18 years to 75 years
People
204 worldwide
Run by
Palisade Bio
See details and how to joinNCT07845487
Phase 3Taking people
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Where
Hradec Králové
Age
16 years to 80 years
People
751 worldwide
Run by
Sanofi
See details and how to joinNCT07185009
Phase 2Taking people
A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis
Where
Hradec Králové, Prague
Age
18 years to 80 years
People
80 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06636656 · EU 2023-509544-10-00
Phase 3Taking people
Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis
Where
Slaný
Age
18 years to 75 years
People
150 worldwide
Run by
Vanda Pharmaceuticals
See details and how to joinNCT07686081 · EU 2025-524520-22-00
Phase 2Taking people
A Phase 2a Study of the Safety and Efficacy of OD-07656 and of Subsequent Vedolizumab Therapy in Moderately to Severely Active Ulcerative Colitis
Where
Hradec Králové
Age
18 years and over
People
70 worldwide
Run by
Odyssey Therapeutics Inc.
See details and how to join2024-520201-39-00 · EU 2024-520201-39-00
Phase 2Taking people
A Phase 2 Platform Study to Evaluate Therapies for Inflammatory Bowel Disease
Where
Brno-Sever, Brno-Zidenice, Prachatice
Age
18 years and over
People
54 worldwide
Run by
Mirador Therapeutics Inc.
See details and how to join2025-522001-38-00 · EU 2025-522001-38-00
Phase 2Taking people
A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)
Where
Brno, Brno-Sever, Brno-Zidenice, České Budějovice, Hradec Králové, Ostrava, Pardubice, Prague, Prague 5, Slezska Ostrava, Usti Nad Labem
Age
18 years to 75 years
People
192 worldwide
Run by
Takeda
See details and how to joinNCT06764615 · EU 2024-518914-18-00
Phase 3Taking people
A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Where
Prague
Age
2 years to 17 years
People
240 worldwide
Run by
Takeda
See details and how to joinNCT05442567 · EU 2023-509046-36-00
Phase 2Taking people
Safety and Efficacy of OD-07656 and of Subsequent Vedolizumab Therapy in Moderately to Severely Active Ulcerative Colitis
Where
Polička
Age
18 years to 75 years
People
57 worldwide
Run by
Odyssey Therapeutics, Inc.
See details and how to joinNCT06850727