Clinical trials

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164 trials

NCT06506461
Recruiting
Gene Editing For Sickle Cell Disease
Phase 1 · United States · 1 site
Registry update: 15 Oct 2026
NCT07356050
Recruiting
Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease
Not applicable · Ghana, Tanzania, United States · 3 sites
Registry update: 21 Jan 2026
NCT06887907
Recruiting
Phenotypic and Transcriptomic Description of Megakaryocytes in Sickle Cell Patient
Not applicable · France · 1 site
Registry update: 20 Mar 2025
NCT06374238
Recruiting
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
Not applicable · United States · 14 sites
Registry update: 8 Oct 2026
NCT06735625
Recruiting
Pilot Study "AHSP as a Biomarker of Sickle Cell Disease in a Population of Adults and Children"
Not applicable · France · 1 site
Registry update: 2 Apr 2025
NCT06770010
Recruiting
Advancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease
Not applicable · United States · 1 site
Registry update: 13 Feb 2025
NCT06612268
Recruiting
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
Phase 3 · Australia, Belgium, Brazil, Canada, Colombia, Spain, France, United Kingdom, Ghana, Greece, India, Italy, Kenya, Lebanon, Nigeria, Netherlands, Oman, Saudi Arabia, Uganda, United States · 164 sites
Registry update: 17 Sept 2026
NCT07001189
Recruiting
Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients
Not applicable · Guadeloupe · 1 site
Registry update: 3 Jun 2025
NCT06290401
Recruiting
A Socio-ecological Approach for Improving Self-management in Adolescents With SCD
Not applicable · United States · 4 sites
Registry update: 11 May 2026
NCT06578507
Recruiting
Pharmacokinetics, Efficacy and Safety of Twice Daily Dosing Regimen of Hydroxycarbamide Dispersible Tablets in Children With Sickle Cell Disease
Phase 2 · France, French Guiana · 7 sites
Registry update: 1 Oct 2026
NCT06650813
Recruiting
Adapting the FACETS Program to Sickle Cell Disease
Not applicable · France · 2 sites
Registry update: 19 Aug 2025
NCT06609226
Recruiting
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
Phase 3 · Canada, Germany, Egypt, Spain, France, United Kingdom, Ghana, Greece, India, Italy, Kenya, Lebanon, Nigeria, Oman, Saudi Arabia, United States · 101 sites
Registry update: 18 Sept 2026
Conflicting statuses (not updated in the registry for 1 month)
NCT06691867
Recruiting
Integrative Training Program for Pediatric Sickle Cell Pain
Not applicable · United States · 4 sites
Registry update: 14 Nov 2025
NCT06635902
Recruiting
Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease
Phase 2 · United States · 1 site
Registry update: 13 Apr 2026
NCT07177300
Recruiting
Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)
Phase 4 · United States · 1 site
Registry update: 16 Sept 2025
NCT05904093
Recruiting
Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease
Phase 1 · United States · 1 site
Registry update: 5 Nov 2026
NCT06757829
Recruiting
Pulmonary Functions in Sickle Cell Disease: Response to Acu-TENS
Not applicable · Egypt · 1 site
Registry update: 3 Jan 2025
NCT06581900
Recruiting
Study of Vitamin B12 Metabolism in Children With Sickle Cell Disease Exposed to MEOPA
Not applicable · France · 1 site
Registry update: 10 Dec 2025
NCT05383911
Recruiting
Empowering Adolescents and Young Adults With Sickle Cell Disease as Partners in Treatment Decision Making (EMPOWER-AYA)
Not applicable · United States · 1 site
Registry update: 16 Jun 2026
NCT06689800
Recruiting
Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy
Not applicable · United States · 1 site
Registry update: 4 Jun 2026

Ordered by registry start date. Freshness and sponsorship never change the order.