Clinical trials

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342 trials

NCT07854483
Not yet recruiting
C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Systemic Sclerosis (SSc) Refractory to Standard Therapy
Phase 1 · US · 1 site
Registry update: 13 Oct 2026
Fresh (updated this month)
NCT07335562
Not yet recruiting
A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis
Phase 3 · BE, CA, CH, DE, ES, FR, GB, IT, JP, US · 55 sites
Registry update: 18 Sept 2026
Fresh (updated 1 month ago)
NCT07523282
Not yet recruiting
Safety and Preliminary Efficacy of HN2302 in Patients With Autoimmune Diseases
Phase 1 · CN · 1 site
Registry update: 12 Aug 2026
Fresh (updated 2 months ago)
NCT07837986
Not yet recruiting
Investigation of Type I Interferon Excess in Patients With Systemic Autoimmune Diseases and Genetic Type I Interferonopathies
Not applicable · FR · 3 sites
Registry update: 24 Sept 2026
Fresh (updated 1 month ago)
NCT07734012
Not yet recruiting
Mycophenolate After Stem Cell Transplant for Systemic Sclerosis
Phase 2 · CA · 1 site
Registry update: 19 Oct 2026
Fresh (updated this month)
NCT07906145
Not yet recruiting
A Phase 1 Study of QLS2416 Injection in Participants With Autoimmune Diseases
Phase 1 · - · no sites listed
Registry update: 30 Oct 2026
Fresh (updated this month)
NCT07544225
Not yet recruiting
Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic Diseases
Phase 1 · FR · 1 site
Registry update: 2 Sept 2026
Fresh (updated 2 months ago)
NCT07916324
Not yet recruiting
Hyaluronidase Injections for Sclerodactyly in Patients With Scleroderma
Phase 2 · US · 1 site
Registry update: 4 Nov 2026
Fresh (updated this month)
NCT07782450
Not yet recruiting
A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune Diseases
Phase 1/2 · - · no sites listed
Registry update: 1 Oct 2026
Fresh (updated 1 month ago)
NCT07697274
Not yet recruiting
Hyaluronidase for Sclerodactyly in Systemic Sclerosis Trial
Early phase 1 · US · 1 site
Registry update: 16 Oct 2026
Fresh (updated this month)
NCT07821398
Not yet recruiting
Hyperpolarized Xenon MRI in Adults With Pulmonary Hypertension in Interstitial Lung Disease and Systemic Sclerosis
Phase 2 · - · no sites listed
Registry update: 15 Sept 2026
Fresh (updated 1 month ago)
NCT07209644
Not yet recruiting
Catestatin as a Novel Biomarker for Cardiovascular and Microvascular Involvement in Systemic Sclerosis
Not applicable · - · no sites listed
Registry update: 7 Oct 2025
Stale (updated 12 months ago)
NCT07888842
Not yet recruiting
A Clinical Study on Systemic Sclerosis and the Validation of French-language Questionnaires Assessing Disability, Quality of Life, and Disease Status.
Not applicable · FR · 1 site
Registry update: 22 Oct 2026
Fresh (updated this month)
NCT06821659
Not yet recruiting
Safety and Efficacy of Universal CAR-T Cells (UWD-CD19) Combined With Immunosuppressants in the Treatment of Refractory Autoimmune Diseases
Phase 1/2 · - · no sites listed
Registry update: 23 Sept 2026
Fresh (updated 1 month ago)
NCT07842523
Not yet recruiting
Obinutuzumab in Systemic Sclerosis
Phase 2 · FR · 1 site
Registry update: 25 Sept 2026
Fresh (updated 1 month ago)
NCT07858838
Not yet recruiting
Using AI-Assisted Cameras to Track Hand Exercises in Scleroderma Patients
Not applicable · - · 1 site
Registry update: 14 Oct 2026
Fresh (updated this month)
NCT07873931
Not yet recruiting
A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases
Phase 1 · BE, DE, FR, NL, PL, US · 23 sites
Registry update: 14 Oct 2026
Fresh (updated this month)
2025-523288-39-00
Recruiting
Evaluation of MTX-474 in Participants with Diffuse Cutaneous Systemic Sclerosis (dcSSc)
Phase 2 · ES, FR, IT, NL, PL, RO · 26 sites
Registry update: 14 Oct 2026
Fresh (updated this month)
NCT07650565
Recruiting
Tissue Modeling in Systemic Sclerosis Using Induced Pluripotent Stem Cells (iPSCs)
Not applicable · FR · 1 site
Registry update: 29 Oct 2026
Fresh (updated this month)
NCT07748000
Not yet recruiting
A Study of LIQ861 (Inhaled Treprostinil) in Adults With Systemic Sclerosis Who Have Symptomatic Raynaud's Phenomenon Attacks
Phase 2 · - · no sites listed
Registry update: 7 Aug 2026
Fresh (updated 2 months ago)

Ordered by registry start date. Freshness and sponsorship never change the order.