What does science say about Fasting and fasting-mimicking diet and Obesity?
- We don’t say yes or no. We show what has been studied.
- Working in a lab or in animals does not mean it works in people.
- Don’t stop or change your treatment without talking to your doctor.
What has been studied
- Lab studies (cells)Tests on cells in a dish.Source: PubMed · as of 6 Nov 2026 · Open the search at PubMed16studies
- Animal studiesTests in mice, rats or other animals.Source: PubMed · as of 6 Nov 2026 · Open the search at PubMed633studies
- Studies in peoplePublished studies with human participants.Source: PubMed · as of 6 Nov 2026 · Open the search at PubMed2183studies
- Registered trials in peopleTrials entered in a public registry, whatever their result.ClinicalTrials.gov: 43 · as of 6 Nov 2026 · Open the search at ClinicalTrials.govEU CTIS: 0 · as of 6 Nov 2026 · Open the search at EU CTISBy phase:No phase (42)Phase 4 (1)By status:Completed (16)Recruiting (15)Running, not recruiting (6)Not yet recruiting (5)By invitation only (1)Countries (17):United States (13)Egypt (4)China (3)Switzerland (2)Colombia (2)Germany (2)Spain (2)Italy (2)Jordan (2)Netherlands (2)Brazil (1)Chile (1)Czechia (1)Denmark (1)France (1)Indonesia (1)Mexico (1)With a linked publication (results): 7 of 43The registries do not tell us here whether results were posted; a linked publication is shown instead.43trials
- Approved treatmentApproved by a medicines regulator for this disease.No
Examples of what we found
The trials
No phase
NutrImmune: Precision Nutrition to Improve Immunity in Individuals With Obesity
Not yet recruiting · Germany, France, Netherlands
ClinicalTrials.gov · NCT07850206No phase
Influence of the Use of Specific Nutritional Formulas on Time in Range in Patients With Type 2 Diabetes
Not yet recruiting · Colombia
ClinicalTrials.gov · NCT07666581No phase
EndoSense: Continuous Real-Time Monitoring of Health Markers in Endocrine and Metabolic Disorders
Running, not recruiting · Switzerland
ClinicalTrials.gov · NCT07727356No phase
Time-restricted Eating for Postpartum Weight Loss
Recruiting · United States
ClinicalTrials.gov · NCT06491537No phase
Adaptation of Human Brown Adipose Tissue to Calorie Restriction
Running, not recruiting · Spain
ClinicalTrials.gov · NCT06878989No phase
Experimental Approach to Test Predictions of Body Weight Regulation Models
Recruiting · United States
ClinicalTrials.gov · NCT06309576No phase
Thermogenenic Responses to Fasting and Overfeeding in Women
Recruiting · United States
ClinicalTrials.gov · NCT06610162No phase
Intermittent Fasting, Mediterranean Diet and NAFLD
Not yet recruiting
ClinicalTrials.gov · NCT06615817No phase
Longitudinal Monitoring During Intermittent Fasting Protocols in Obese Adults
Recruiting · Switzerland
ClinicalTrials.gov · NCT06323889No phase
Thermogenic Silencer Regulatory Factors in Humans
Running, not recruiting · United States
ClinicalTrials.gov · NCT06424132No phase
Modified Intermittent Eating on Weight Loss (INTEREST-3 Trial)
Recruiting · China
ClinicalTrials.gov · NCT06302803No phase
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
Recruiting · United States
ClinicalTrials.gov · NCT05545306No phase
Intermittent Fasting for NAFLD in Adults
Recruiting · United States
ClinicalTrials.gov · NCT04899102No phase
Daily Caloric Restriction in ADPKD
Running, not recruiting · United States
ClinicalTrials.gov · NCT04907799No phase
Promotion of Weight Management
Running, not recruiting · United States
ClinicalTrials.gov · NCT04131647No phase
Study of Changes in Skeletal Muscle After Caloric Restriction
Running, not recruiting · United States
ClinicalTrials.gov · NCT00993460No phase
PROFAST Intervention in Precursor Multiple Myeloma
Completed · United States
ClinicalTrials.gov · NCT05565638No phase
Prolonged Daily Fasting as a Viable Alternative to Caloric Restriction in At-Risk Obese Humans
Completed · United States
ClinicalTrials.gov · NCT04259632No phase
Alternate Day Fasting, Exercise, and NAFLD
Completed · United States
ClinicalTrials.gov · NCT04004403No phase
Longevity Diet and the Fasting-mimicking Diet
Completed · Italy
ClinicalTrials.gov · NCT07065955
Thinking of paying for it? Read this first
- Ask for published results. Stories, thank-you letters and "patients report" are not results. Ask where the results were published.
- Know what you pay for. Ask in writing: what exactly is included, who gets the money, and what happens if you stop.
- Ask your own doctor first. Some products interfere with chemotherapy, radiation or other medicines. Your treating doctor can check this.
- Do not stop standard treatment for it. Do not stop or delay your treatment without talking to your care team.
Other treatments people ask about
- Cannabis and cannabinoids (CBD, THC)Step: Large trials
- Curcumin (turmeric)Step: Large trials
- Fasting and fasting-mimicking dietStep: Large trials
- High-dose vitamin CStep: Large trials
- HyperthermiaStep: Large trials
- IvermectinStep: Large trials
- Ketogenic dietStep: Large trials
- MelatoninStep: Large trials
- MetforminStep: Large trials
- StatinsStep: Large trials
- Vitamin DStep: Large trials
- Dichloroacetate (DCA)Step: Animal studies only
- FenbendazoleStep: Animal studies only
- Mistletoe extractStep: Animal studies only
Not medical advice. Talk to the care team before changing treatment.