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CBD (cannabidiol) & Prostate cancer

Checked 2026. nov. 11. · Prostate cancer

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Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.

The claim

Posts online say that CBD (cannabidiol) helps with prostate cancer.

Where research stands

We found 9 published papers on CBD (cannabidiol) and prostate cancer. They were published between 2023 and 2026. None of them is a study in people. 5 were studies in animals, and 3 were only in cells in the lab. 1 new study in people is running or will start soon, says the trial register ClinicalTrials.gov.

  • 0In people
  • 5In animals
  • 3Only in the lab

What the studies found

We have not summed up these studies in words yet. The most important papers are listed under Sources.

Verdict

Unproven

CBD (cannabidiol) has been studied for prostate cancer in animals, not yet in people.

Unproven means: it was only tested in animals or cells, or there is too little or mixed data from people. How we rate claims

What this means for you: Results in animals or in cells often do not hold in people. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. Cannabidiol Suppresses Metastatic Castration-Resistant Prostate Cancer Progression and Recurrence through Modulating Tryptophan Catabolism.2024 · ACS Pharmacol Transl Sci · In animals
  2. In Vitro Antitumor Effect of Oils Rich in CBD and THC Cannabis Extract in Canine Prostate Carcinoma Cell Lines.2024 · Vet Sci · In animals
  3. A Phase I Dose Escalation and Expansion Study of Epidiolex (Cannabidiol) in Patients with Biochemically Recurrent Prostate Cancer.2023 · Cancers (Basel) · In animals
  4. Cannabidiol and Cannabis Sativa as a potential treatment in vitro prostate cancer cells silenced with RBBp6 and PC3 xenograft.2023 · Mol Biol Rep · In animals
  5. Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer.2023 · Pharmacol Res · In animals
  6. Cannabidiol alters the epigenome of hormone-dependent prostate cancer cells.2026 · Biomed Pharmacother · In the lab
  7. Cannabidiol Enhances the Anticancer Activity of Etoposide on Prostate Cancer Cells.2025 · Cannabis Cannabinoid Res · In the lab
  8. Cannabidiol Inhibits the Proliferation and Invasiveness of Prostate Cancer Cells.2023 · J Nat Prod · In the lab
  9. Anti-proliferative effect of Cannabidiol in Prostate cancer cell PC3 is mediated by apoptotic cell death, NFκB activation, increased oxidative stress, and lower reduced glutathione status.2023 · PLoS One · Other paper

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