Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.
The claim
Posts online say that CBD (cannabidiol) helps with ulcerative colitis.
Where research stands
We found 7 published papers on CBD (cannabidiol) and ulcerative colitis. They were published between 2011 and 2026. 1 of them is a study in people. 1 of them compared people who got it with a group that did not. 6 were studies in animals, and none was only in cells in the lab.
- 1In people1 with a comparison group
- 6In animals
- 0Only in the lab
What the studies found
We have not summed up these studies in words yet. The most important papers are listed under Sources.
Verdict
CBD (cannabidiol) has been tested in randomised trials in people with ulcerative colitis.
What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- A Randomized, Double-blind, Placebo-controlled, Parallel-group, Pilot Study of Cannabidiol-rich Botanical Extract in the Symptomatic Treatment of Ulcerative Colitis.2018 · Inflamm Bowel Dis · Randomised trial
- A novel enema formulation containing cannabidiol and sodium propionate for ulcerative colitis: preclinical assessment in a murine model.2026 · J Cannabis Res · In animals
- Orally Administered CBD/CBG Hemp Extract Reduces Severity of Ulcerative Colitis and Pain in a Murine Model.2025 · J Clin Med · In animals
- Cannabidiol Alleviates Intestinal Fibrosis in Mice with Ulcerative Colitis by Regulating Transforming Growth Factor Signaling Pathway.2025 · J Inflamm Res · In animals
- Comprehensive Assessment of Cannabidiol and HU308 in Acute and Chronic Colitis Models: Efficacy, Safety, and Mechanistic Innovations.2024 · Cells · In animals
- Multi-targeting inulin-based nanoparticles with cannabidiol for effective prevention of ulcerative colitis.2024 · Mater Today Bio · In animals
- Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.2011 · PLoS One · In animals
