Curcumin (turmeric) & Cystic fibrosis

Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.

What people read

Posts online say that Curcumin (turmeric) helps with Cystic fibrosis.

What has been studied

• 3In people2 randomised trials
• 5In animals
• 9Only in the lab

What the studies found

!Curcumin (turmeric) has been tested in randomised trials in people with Cystic fibrosis.

We found 29 published papers on Curcumin (turmeric) and Cystic fibrosis. They were published between 2004 and 2025.

3 of them are studies in people (2 randomised trials), 4 are reviews, 5 are studies in animals and 9 are studies only in the lab.

The most important ones are listed under Sources.

Sources

1. Adjunctive nano-curcumin therapy improves inflammatory and clinical indices in children with cystic fibrosis: A randomized clinical trial.2023 · Food Sci Nutr · Randomised trial
2. The effects of nano-curcumin as a nutritional strategy on clinical and inflammatory factors in children with cystic fibrosis: the study protocol for a randomized controlled trial.2021 · Trials · Randomised trial
3. Clinical effects of the three CFTR potentiator treatments curcumin, genistein and ivacaftor in patients with the CFTR-S1251N gating mutation.2020 · J Cyst Fibros · Study in people
4. Therapeutic applications of curcumin nanomedicine formulations in cystic fibrosis.2022 · Prog Biomater · Review
5. Curcumin and genistein: the combined effects on disease-associated CFTR mutants and their clinical implications.2013 · Curr Pharm Des · Review
6. Correction of the CF defect by curcumin: hypes and disappointments.2005 · Bioessays · Review
7. Some like it hot: curcumin and CFTR.2004 · Trends Mol Med · Review
8. Curcumin-mediated NRF2 induction limits inflammatory damage in, preclinical models of cystic fibrosis.2025 · Biomed Pharmacother · In animals
9. Curcumin stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity.2005 · J Biol Chem · In animals
10. Curcumin does not stimulate cAMP-mediated chloride transport in cystic fibrosis airway epithelial cells.2004 · Biochem Biophys Res Commun · In animals
11. Can curcumin cure cystic fibrosis?2004 · N Engl J Med · In animals
12. Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models.2004 · J Biol Chem · In animals
13. Curcumin Down-Regulates Toll-Like Receptor-2 Gene Expression and Function in Human Cystic Fibrosis Bronchial Epithelial Cells.2019 · Biol Pharm Bull · In the lab
14. External Zn(2+) binding to cysteine-substituted cystic fibrosis transmembrane conductance regulator constructs regulates channel gating and curcumin potentiation.2016 · FEBS J · In the lab
15. Molecular Basis for Fe(III)-Independent Curcumin Potentiation of Cystic Fibrosis Transmembrane Conductance Regulator Activity.2015 · Biochemistry · In the lab
16. Interplay between inhibitory ferric and stimulatory curcumin regulates phosphorylation-dependent human cystic fibrosis transmembrane conductance regulator and ΔF508 activity.2015 · Biochemistry · In the lab
17. Silibinins and curcumin as promising ligands against mutant cystic fibrosis transmembrane regulator protein.2024 · AMB Express · Other paper
18. Correction to Molecular Basis for Fe(III)-Independent Curcumin Potentiation of Cystic Fibrosis Transmembrane Conductance Regulator Activity.2015 · Biochemistry · Other paper
19. [Effects of Imipenem, Tobramycin and Curcumin on Biofilm Formation of Pseudomonas aeruginosa Strains].2013 · Mikrobiyol Bul · Other paper
20. Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin.2010 · Mol Pharm · Other paper

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