Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.
The claim
Posts online say that vitamin C (incl. high-dose) helps with acute lymphoblastic leukaemia.
Where research stands
We found 8 published papers on vitamin C (incl. high-dose) and acute lymphoblastic leukaemia in PubMed. They were published between 1975 and 2025. None of them is a study in people. 3 were studies in animals, and none was only in cells in the lab.
- 0In people
- 3In animals
- 0Only in the lab
What the studies found
We have not summed up these studies in words yet. The most important papers are listed under Sources.
Verdict
Vitamin C (incl. high-dose) has been studied for acute lymphoblastic leukaemia in animals, not yet in people.
Unproven means: it was only tested in animals or cells, or there is too little or mixed data from people. How we rate claims
What this means for you: Results in animals or in cells often do not hold in people. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- High-dose vitamin C potently induces apoptosis in acute lymphoblastic leukemia by activating ER stress response.2025 · Hum Exp Toxicol · In animals
- Association of Leukemia Target Genes Tet2, Bcl2, and Slc23a2 in Vitamin C Pathways.2019 · Cancer Genomics Proteomics · In animals
- Stromal cell oxidation: a mechanism by which tumors obtain vitamin C.1999 · Cancer Res · In animals
- Vitamin C status in Iranian children with acute lymphoblastic leukemia: evidence for increased utilization.2007 · J Pediatr Gastroenterol Nutr · Other paper
- The association between vitamin C and vitamin E supplement use before hematopoietic stem cell transplant and outcomes to two years.2003 · J Am Diet Assoc · Other paper
- Effect of chemotherapy on ascorbate and ascorbyl radical in cerebrospinal fluid and serum of acute lymphoblastic leukemia.2000 · Cell Mol Biol (Noisy-le-grand) · Other paper
- Plasma and leucocyte ascorbic acid concentrations in acute lymphoblastic leukaemia.1975 · Ir J Med Sci · Other paper
