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Vitamin C (incl. high-dose) & Chronic lymphocytic leukaemia

Checked 2026. nov. 11. · Chronic lymphocytic leukaemia

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Written based on 5 research studies on PubMed, searched on 2026. nov. 11..

The claim

Posts online say that vitamin C (incl. high-dose) helps with chronic lymphocytic leukaemia.

Where research stands

We found 5 published papers on vitamin C (incl. high-dose) and chronic lymphocytic leukaemia. They were published between 1981 and 2020. 1 of them is a study in people. None of them compared people who got it with a group that did not. None was a study in animals, and 2 were only in cells in the lab.

  • 1In people
  • 0In animals
  • 2Only in the lab

What the studies found

We have not summed up these studies in words yet. The most important papers are listed under Sources.

Verdict

Vitamin C (incl. high-dose) has been studied in people with chronic lymphocytic leukaemia, but not in randomised trials.

What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. Phase II study of arsenic trioxide and ascorbic acid for relapsed or refractory lymphoid malignancies: a Wisconsin Oncology Network study.2009 · Hematol Oncol · Study in people
  2. Ascorbic acid (vitamin C) synergistically enhances the therapeutic effect of targeted therapy in chronic lymphocytic leukemia.2020 · J Exp Clin Cancer Res · In the lab
  3. Arsenic trioxide and ascorbic acid demonstrate promising activity against primary human CLL cells in vitro.2010 · Leuk Res · In the lab
  4. Fruit and vegetable intake and vitamin C transporter gene (SLC23A2) polymorphisms in chronic lymphocytic leukaemia.2017 · Eur J Nutr · Other paper
  5. Increased ascorbic acid content in chronic lymphocytic leukemia B lymphocytes.1981 · Proc Natl Acad Sci U S A · Other paper

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