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Vitamin C (incl. high-dose) & Neuroblastoma

Checked 2026. nov. 11. · Neuroblastoma

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Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.

What people read

Posts online say that vitamin C (incl. high-dose) helps with neuroblastoma.

What has been studied

  • 0In people
  • 5In animals
  • 20Only in the lab

What the studies found

Vitamin C (incl. high-dose) has been studied for neuroblastoma in animals, not yet in people.

We found 26 published papers on vitamin C (incl. high-dose) and neuroblastoma. They were published between 1979 and 2017.

0 of them are studies in people (0 randomised trials), 0 are reviews, 5 are studies in animals and 20 are studies only in the lab.

The most important ones are listed under Sources.

What this means for you: Results in animals or in cells often do not hold in people. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage and reduction in cancer cell glycolysis.2017 · Free Radic Biol Med · In animals
  2. Melatonin, minocycline and ascorbic acid reduce oxidative stress and viral titers and increase survival rate in experimental Venezuelan equine encephalitis.2015 · Brain Res · In animals
  3. Nutrient mixture including vitamin C, L-lysine, L-proline, and epigallocatechin is ineffective against tumor growth and metastasis in a syngeneic neuroblastoma model.2008 · Pediatr Blood Cancer · In animals
  4. Synthesis and release of vasoactive intestinal polypeptide (VIP) by mouse neuroblastoma cells: modulation by cyclic nucleotides and ascorbic acid.1985 · Peptides · In animals
  5. Sodium ascorbate potentiates the growth inhibitory effect of certain agents on neuroblastoma cells in culture.1979 · Proc Natl Acad Sci U S A · In animals
  6. Effect of ascorbic acid and hydrogen peroxide on mouse neuroblastoma cells.2012 · Mol Med Rep · In the lab
  7. Identification of SUMOylated proteins in neuroblastoma cells after treatment with hydrogen peroxide or ascorbate.2010 · BMB Rep · In the lab
  8. Sodium ascorbate induces apoptosis in neuroblastoma cell lines by interfering with iron uptake.2007 · Mol Cancer · In the lab
  9. Comparison of melatonin versus vitamin C on oxidative stress and antioxidant enzyme activity in Alzheimer's disease induced by okadaic acid in neuroblastoma cells.2002 · Eur J Pharmacol · In the lab
  10. Ascorbate suppresses the opiate-induced compensatory increase in cyclic AMP in neuroblastoma X glioma hybrid cells.1982 · Biochem J · Other paper

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