Written based on 15 research studies on PubMed, searched on 2026. nov. 14..
The claim
Posts online say that omega-3 fatty acids (fish oil) helps with aortic aneurysm.
Where research stands
We found 16 published papers on omega-3 fatty acids (fish oil) and aortic aneurysm. They were published between 1996 and 2026. 3 of them are studies in people. 2 of them compared people who got it with a group that did not. 7 were studies in animals, and 1 was only in cells in the lab. 2 papers are reviews that sum up other studies.
- 3In people2 with a comparison group
- 7In animals
- 1Only in the lab
What the studies found
We have not summed up these studies in words yet. The most important papers are listed under Sources.
Verdict
Omega-3 fatty acids (fish oil) has been tested in randomised trials in people with aortic aneurysm.
What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- Long Chain Omega-3 Polyunsaturated Fatty Acids Improve Vascular Stiffness in Abdominal Aortic Aneurysm: A Randomized Controlled Trial.2020 · Nutrients · Randomised trial
- Fish oil after abdominal aorta aneurysm surgery.2008 · Eur J Clin Nutr · Randomised trial
- The long-term effect of eicosapentaenoic acid on serum levels of lipoprotein (a) and lipids in patients with vascular disease.1996 · J Atheroscler Thromb · Study in people
- Drug Therapy for Abdominal Aortic Aneurysms Utilizing Omega-3 Unsaturated Fatty Acids and Their Derivatives.2018 · Curr Drug Targets · Review
- Abdominal aortic aneurysm and omega-3 polyunsaturated fatty acids: Mechanisms, animal models, and potential treatment.2017 · Prostaglandins Leukot Essent Fatty Acids · Review
- Eicosapentaenoic acid is associated with the attenuation of dysfunctions of mesenchymal stem cells in the abdominal aortic aneurysm wall.2022 · Food Funct · In animals
- Similar distribution of orally administered eicosapentaenoic acid and M2 macrophage marker in the hypoperfusion-induced abdominal aortic aneurysm wall.2021 · Food Funct · In animals
- Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice.2017 · Food Funct · In animals
- The preventive effect of fish oil on abdominal aortic aneurysm development.2016 · Biosci Biotechnol Biochem · In animals
- Omega 3 Polyunsaturated Fatty Acids Suppress the Development of Aortic Aneurysms Through the Inhibition of Macrophage-Mediated Inflammation.2015 · Circ J · In animals
- Dietary supplementation with omega-3 polyunsaturated fatty acids modulate matrix metalloproteinase immunoreactivity in a mouse model of pre-abdominal aortic aneurysm.2015 · Heart Lung Circ · In animals
- NLRP3+ Macrophages: Central Inflammatory Nodes of Abdominal Aortic Aneurysm and Potential Cellular Target of Omega-3 Polyunsaturated Fatty Acids.2026 · Food Sci Nutr · In the lab
- Characteristic distribution of eicosapentaenoic acid in human abdominal aortic aneurysm wall.2022 · J Lipid Res · Other paper
- Omega-3 fatty acids decrease oxidative stress and inflammation in macrophages from patients with small abdominal aortic aneurysm.2019 · Sci Rep · Other paper
- Arachidonic Acid, but Not Omega-3 Index, Relates to the Prevalence and Progression of Abdominal Aortic Aneurysm in a Population-Based Study of Danish Men.2018 · J Am Heart Assoc · Other paper
