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Omega-3 fatty acids (fish oil) & Duchenne muscular dystrophy

Checked 2026. nov. 11. · Duchenne muscular dystrophy

Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.

What people read

Posts online say that Omega-3 fatty acids (fish oil) helps with Duchenne muscular dystrophy.

What has been studied

  • 3In people3 randomised trials
  • 6In animals
  • 0Only in the lab

What the studies found

Omega-3 fatty acids (fish oil) has been tested in randomised trials in people with Duchenne muscular dystrophy.

We found 9 published papers on Omega-3 fatty acids (fish oil) and Duchenne muscular dystrophy. They were published between 2013 and 2025.

3 of them are studies in people (3 randomised trials), 0 are reviews, 6 are studies in animals and 0 are studies only in the lab.

The most important ones are listed under Sources.

What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. Pro-inflammatory monocytes are increased in Duchenne muscular dystrophy and suppressed with omega-3 fatty acids: A double-blind, randomized, placebo-controlled pilot study.2022 · Eur J Neurol · Randomised trial
  2. Evidence of muscle loss delay and improvement of hyperinsulinemia and insulin resistance in Duchenne muscular dystrophy supplemented with omega-3 fatty acids: A randomized study.2019 · Clin Nutr · Randomised trial
  3. Potential therapeutic impact of omega-3 long chain-polyunsaturated fatty acids on inflammation markers in Duchenne muscular dystrophy: A double-blind, controlled randomized trial.2018 · Clin Nutr · Randomised trial
  4. Exercise combined with corticoid/omega-3 therapy positively affected skeletal and cardiac muscles in middle aged mdx mice.2025 · Int J Exp Pathol · In animals
  5. Identification of plasma interleukins as biomarkers for deflazacort and omega-3 based Duchenne muscular dystrophy therapy.2018 · Cytokine · In animals
  6. Effects of dietary omega-3 on dystrophic cardiac and diaphragm muscles as evaluated by 1H magnetic resonance spectroscopy: Metabolic profile and calcium-related proteins.2017 · Clin Nutr ESPEN · In animals
  7. Effects of fish oil containing eicosapentaenoic acid and docosahexaenoic acid on dystrophic mdx mice hearts at later stages of dystrophy.2016 · Nutrition · In animals
  8. Long-Term Therapy With Omega-3 Ameliorates Myonecrosis and Benefits Skeletal Muscle Regeneration in Mdx Mice.2015 · Anat Rec (Hoboken) · In animals
  9. Effects of fish oil containing eicosapentaenoic acid and docosahexaenoic acid on dystrophic mdx mice.2013 · Clin Nutr · In animals

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