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Omega-3 fatty acids (fish oil) & Glaucoma

Checked 2026. nov. 11. · Glaucoma

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Written based on 12 research studies on PubMed, searched on 2026. nov. 11..

The claim

Posts online say that omega-3 fatty acids (fish oil) helps with glaucoma.

Where research stands

We found 15 published papers on omega-3 fatty acids (fish oil) and glaucoma. They were published between 2009 and 2026. 3 of them are studies in people. 2 of them compared people who got it with a group that did not. 3 were studies in animals, and 1 was only in cells in the lab. 1 paper is a review that sums up other studies.

  • 3In people2 with a comparison group
  • 3In animals
  • 1Only in the lab

What the studies found

We have not summed up these studies in words yet. The most important papers are listed under Sources.

Verdict

Omega-3 fatty acids (fish oil) has been tested in randomised trials in people with glaucoma.

What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. The Effect of Oral Citicoline and Docosahexaenoic Acid on the Visual Field of Patients with Glaucoma: A Randomized Trial.2022 · Life (Basel) · Randomised trial
  2. Effects of Oral Supplementation with Docosahexaenoic Acid (DHA) plus Antioxidants in Pseudoexfoliative Glaucoma: A 6-Month Open-Label Randomized Trial.2018 · J Ophthalmol · Randomised trial
  3. Omega-3 fatty acid supplementation improves dry eye symptoms in patients with glaucoma: results of a prospective multicenter study.2016 · Clin Ophthalmol · Study in people
  4. Fish Oil in Glaucoma Treatment: From Biological Functions to Clinical Potential.2023 · Mol Nutr Food Res · Review
  5. Effects of topical docosahexaenoic acid on postoperative fibrosis in an animal model of glaucoma filtration surgery.2023 · Acta Ophthalmol · In animals
  6. Short-Term Omega-3 Supplementation Modulates Novel Neurovascular and Fatty Acid Metabolic Proteome Changes in the Retina and Ophthalmic Artery of Mice with Targeted Cyp2c44 Gene Deletion.2022 · Cells · In animals
  7. Omega-3 fatty acids protect retinal neurons in the DBA/2J hereditary glaucoma mouse model.2018 · Exp Eye Res · In animals
  8. Preventive effects of omega-3 and omega-6 Fatty acids on peroxide mediated oxidative stress responses in primary human trabecular meshwork cells.2012 · PLoS One · In the lab
  9. Relationship Between Omega-3 Fatty Acids and Glaucoma Risk in Patients With Dry Eye Disease: A Multinational Retrospective Cohort Study.2026 · Transl Vis Sci Technol · Other paper
  10. Letter to the Editor: Preliminary evaluation on effect of oral omega-3 supplementation from herring caviar oil in primary open angle glaucoma patients.2025 · Int Ophthalmol · Other paper
  11. Association of Plasma Omega-3 Fatty Acids With POAG.2025 · Invest Ophthalmol Vis Sci · Other paper
  12. Preliminary evaluation on the effect of oral omega-3 supplementation from herring caviar oil in primary open-angle glaucoma patients.2025 · Int Ophthalmol · Other paper

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