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Omega-3 fatty acids (fish oil) & Polycystic kidney disease

Checked 2026. nov. 11. · Polycystic kidney disease

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Written based on 5 research studies on PubMed, searched on 2026. nov. 11..

The claim

Posts online say that omega-3 fatty acids (fish oil) helps with polycystic kidney disease.

Where research stands

We found 5 published papers on omega-3 fatty acids (fish oil) and polycystic kidney disease. They were published between 2008 and 2022. 1 of them is a study in people. 1 of them compared people who got it with a group that did not. 4 were studies in animals, and none was only in cells in the lab.

  • 1In people1 with a comparison group
  • 4In animals
  • 0Only in the lab

What the studies found

We have not summed up these studies in words yet. The most important papers are listed under Sources.

Verdict

Omega-3 fatty acids (fish oil) has been tested in randomised trials in people with polycystic kidney disease.

What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. The effect of eicosapentaenoic acid on renal function and volume in patients with ADPKD.2008 · Nephrol Dial Transplant · Randomised trial
  2. Renoprotective effects of docosahexaenoic acid in cats with early chronic kidney disease due to polycystic kidney disease: a pilot study.2022 · J Feline Med Surg · In animals
  3. Distinct effects of dietary flax compared to fish oil, soy protein compared to casein, and sex on the renal oxylipin profile in models of polycystic kidney disease.2017 · Prostaglandins Leukot Essent Fatty Acids · In animals
  4. Lack of Benefit of Early Intervention with Dietary Flax and Fish Oil and Soy Protein in Orthologous Rodent Models of Human Hereditary Polycystic Kidney Disease.2016 · PLoS One · In animals
  5. Feeding soy protein isolate and oils rich in omega-3 polyunsaturated fatty acids affected mineral balance, but not bone in a rat model of autosomal recessive polycystic kidney disease.2015 · BMC Nephrol · In animals

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