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Stem cell treatment & Aortic stenosis

Checked 2026. nov. 14. · Aortic stenosis

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Written based on 7 research studies on PubMed, searched on 2026. nov. 14..

The claim

Posts online say that stem cell treatment helps with aortic stenosis.

Where research stands

We found 8 published papers on stem cell treatment and aortic stenosis. They were published between 2012 and 2026. None of them is a study in people. 1 was a study in animals, and 5 were only in cells in the lab. 1 paper is a review that sums up other studies. 2 research projects on stem cell treatment for aortic stenosis are funded and still running.

  • 0In people
  • 1In animals
  • 5Only in the lab

What the studies found

We have not summed up these studies in words yet. The most important papers are listed under Sources.

Verdict

Unproven

Stem cell treatment has been studied for aortic stenosis in animals, not yet in people.

Unproven means: it was only tested in animals or cells, or there is too little or mixed data from people. How we rate claims

What this means for you: Results in animals or in cells often do not hold in people. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. Vascular disease modeling using induced pluripotent stem cells: Focus in Hutchinson-Gilford Progeria Syndrome.2016 · Biochem Biophys Res Commun · Review
  2. Exosomal NAMPT from Engineered Mesenchymal Stem Cells Mitigates Aortic Stenosis via Metabolic and Anti-Inflammatory Pathways.2025 · Int J Mol Sci · In animals
  3. Mesenchymal Stem Cells of Epicardial Adipose Tissue Show Differences in Immunophenotype and Osteogenic Potential in Patients with Coronary and Non-Coronary Heart Disease.2026 · Cells · In the lab
  4. Transcriptomic Analysis of Mineralized Adipose-Derived Stem Cell Tissues for Calcific Valve Disease Modelling.2024 · Int J Mol Sci · In the lab
  5. Generation of an induced pluripotent stem cell line (ITXi012-A) from a patient with genetically determined high-lipoprotein(a) plasma levels.2023 · Stem Cell Res · In the lab
  6. Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties.2019 · Sci Rep · In the lab
  7. Cardiac Mesenchymal Stem Cell-like Cells Derived from a Young Patient with Bicuspid Aortic Valve Disease Have a Prematurely Aged Phenotype.2022 · Biomedicines · Other paper

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