Written based on 22 research studies on PubMed, searched on 2026. nov. 11..
The claim
Posts online say that stem cell treatment helps with atopic dermatitis (eczema).
Where research stands
We found 77 published papers on stem cell treatment and atopic dermatitis (eczema). They were published between 2001 and 2026. 2 of them are studies in people. 2 of them compared people who got it with a group that did not. 44 were studies in animals, and 4 were only in cells in the lab. 10 papers are reviews that sum up other studies. 4 research projects on stem cell treatment for atopic dermatitis (eczema) are funded and still running.
- 2In people2 with a comparison group
- 44In animals
- 4Only in the lab
What the studies found
We have not summed up these studies in words yet. The most important papers are listed under Sources.
Verdict
Stem cell treatment has been tested in randomised trials in people with atopic dermatitis (eczema).
What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- Efficacy and safety of autologous adipose-derived stem cells in subjects with moderate to severe atopic dermatitis: a multicenter, randomized, single-blind, placebo-controlled, phase 2 trial.2025 · Stem Cell Res Ther · Randomised trial
- Phase 1/2 trials of human bone marrow-derived clonal mesenchymal stem cells for treatment of adults with moderate to severe atopic dermatitis.2024 · J Allergy Clin Immunol · Randomised trial
- The Potential Role of Mesenchymal Stem Cell Therapy for Moderate-to-Severe Atopic Dermatitis: A Systematic Review and Meta-Analysis of Human Clinical Trials.2026 · Stem Cells Dev · Review
- Adipose-derived mesenchymal stem cells and their derivatives in inflammatory skin diseases: a systematic review.2025 · Front Immunol · Review
- Therapeutic roles of natural and engineered mesenchymal stem cells and extracellular vesicles in atopic dermatitis.2025 · Regen Ther · Review
- Mesenchymal Stromal Cell-Derived Extracellular Vesicles in the Management of Atopic Dermatitis: A Scoping Review of Therapeutic Opportunities and Challenges.2025 · Int J Nanomedicine · Review
- Therapeutic Potential and Mechanisms of Mesenchymal Stem Cell and Mesenchymal Stem Cell-Derived Extracellular Vesicles in Atopic Dermatitis.2024 · J Inflamm Res · Review
- Therapeutic effects of mesenchymal stem cells and their derivatives in common skin inflammatory diseases: Atopic dermatitis and psoriasis.2023 · Front Immunol · Review
- Interleukin-37 overexpression enhances the therapeutic efficacy of adipose-derived mesenchymal stem cells in atopic dermatitis by activating autophagy and improving skin barrier dysfunction.2026 · J Pharmacol Exp Ther · In animals
- Umbilical cord mesenchymal stem cell-derived exosomes delivered via a thermosensitive hydrogel ameliorate atopic dermatitis by mitigating keratinocyte mitochondrial damage through activating the Wnt/β-catenin pathway.2026 · Int Immunopharmacol · In animals
- Hypoxic conditioning induced by CoCl2 enhanced the therapeutic effects of mesenchymal stem cell-derived exosomes on oxazolone-induced atopic dermatitis-like skin lesions in BALB/c mice.2026 · Mol Immunol · In animals
- Conditioned medium from stem cells of human exfoliated deciduous teeth ameliorates mouse ovalbumin-specific allergic dermatitis.2025 · Stem Cell Res Ther · In animals
- Mesenchymal stem cell-derived extracellular vesicles exert Th1-mediated anti-inflammatory effects via miR-146a/NF-κB pathway: comparison with dupilumab in a mouse model of atopic dermatitis.2025 · Stem Cell Res Ther · In animals
- Neural stem cell-derived extracellular vesicles alleviate inflammatory responses in a mouse model of atopic dermatitis.2025 · Stem Cells · In animals
- Sustained release of stem cell secretome from nano-villi chitosan microspheres for effective treatment of atopic dermatitis.2024 · Int J Biol Macromol · In the lab
- Human Induced Pluripotent Stem Cell-Derived Keratinocyte-Like Cells for Research on Protease-Activated Receptor 2 in Nonhistaminergic Cascades of Atopic Dermatitis .2023 · J Pharmacol Exp Ther · In the lab
- T helper (Th)1, Th17 and Th2 imbalance in mesenchymal stem cells of adult patients with atopic dermatitis: at the origin of the problem.2017 · Br J Dermatol · In the lab
- Vasoactive intestinal peptide and cytokines enhance stem cell factor production from epidermal keratinocytes DJM-1.2002 · J Invest Dermatol · In the lab
- Case Report: Intravenous transplantation of autologous adipose tissue-derived mesenchymal stem cells attenuated atopic dermatitis.2026 · Front Med (Lausanne) · Other paper
- Skin microbiome analysis of a junctional epidermolysis bullosa patient treated with genetically modified stem cells.2025 · J Dtsch Dermatol Ges · Other paper
- Correction to: TGF-β secreted by human umbilical cord blood-derived mesenchymal stem cells ameliorates atopic dermatitis by inhibiting secretion of TNF-α and IgE.2023 · Stem Cells · Other paper
- Adipose-derived stem cell exosomes for treatment of dupilumab-related facial redness in patients with atopic dermatitis.2023 · J Dermatolog Treat · Other paper
