Stem cell treatment & Brain aneurysm

Written based on 18 research studies on PubMed, searched on 2026. nov. 15..

The claim

Posts online say that stem cell treatment helps with brain aneurysm.

Where research stands

We found 21 published papers on stem cell treatment and brain aneurysm. They were published between 2004 and 2025. None of them is a study in people. 8 were studies in animals, and 2 were only in cells in the lab. 7 papers are reviews that sum up other studies.

• 0In people
• 8In animals
• 2Only in the lab

What the studies found

We have not summed up these studies in words yet. The most important papers are listed under Sources.

Verdict

Unproven means: it was only tested in animals or cells, or there is too little or mixed data from people. How we rate claims

Sources

1. The mechanisms and applications of endothelial progenitor cell therapy in the treatment of intracranial aneurysm.2025 · J Transl Med · Review
2. Current Applications and Future Directions for Vascular Stents with Stem Cells in the Treatment of Intracranial Aneurysms: A Mini-Review.2025 · Curr Stem Cell Res Ther · Review
3. Promise of mesenchymal stem cell-derived extracellular vesicles for alleviating subarachnoid hemorrhage-induced brain dysfunction by neuroprotective and antiinflammatory effects.2024 · Brain Behav Immun Health · Review
4. Intravenous Stem Cell Therapy for High-Grade Aneurysmal Subarachnoid Hemorrhage: Case Report and Literature Review.2019 · World Neurosurg · Review
5. Nanoparticles and stem cells - has targeted therapy for aneurysms finally arrived?2015 · Neurol Res · Review
6. Cerebral aneurysm as an exacerbating factor in stroke pathology and a therapeutic target for neuroprotection.2012 · Curr Pharm Des · Review
7. Mesenchymal stem cells-derived exosomes modulate vascular endothelial injury via miR-144-5p/PTEN in intracranial aneurysm.2021 · Hum Cell · In animals
8. Exosomal microRNA-23b-3p from bone marrow mesenchymal stem cells maintains T helper/Treg balance by downregulating the PI3k/Akt/NF-κB signaling pathway in intracranial aneurysm.2020 · Brain Res Bull · In animals
9. Autologous adipose-derived mesenchymal stem cells improve healing of coiled experimental saccular aneurysms: an angiographic and histopathological study.2018 · J Neurointerv Surg · In animals
10. Protective Effect of Mesenchymal Stem Cells Against the Development of Intracranial Aneurysm Rupture in Mice.2017 · Neurosurgery · In animals
11. Combined endovascular coiling and intra-aneurysmal allogeneic mesenchymal stromal cell therapy for intracranial aneurysms in a rabbit model: a proof-of-concept study.2017 · J Neurointerv Surg · In animals
12. Human Mesenchymal Stem Cell-Derived Microvesicles Prevent the Rupture of Intracranial Aneurysm in Part by Suppression of Mast Cell Activation via a PGE2-Dependent Mechanism.2016 · Stem Cells · In animals
13. A novel tissue engineering approach using an endothelial progenitor cell-seeded biopolymer to treat intracranial saccular aneurysms.2012 · J Neurosurg · In the lab
14. Activation of endogenous neural stem cells in the adult human brain following subarachnoid hemorrhage.2007 · J Neurosci Res · In the lab
15. [Ruptured mycotic cerebral aneurysm in an adult T-cell leukemia/lymphoma patient undergoing allogeneic stem cell transplantation].2024 · Rinsho Ketsueki · Other paper
16. Comparison of Gelatin/Polylysine- and Silk Fibroin/SDF-1α-Coated Mesenchymal Stem Cell-Seeded Intracranial Stents.2023 · Macromol Biosci · Other paper
17. Correction to: Mesenchymal stem cells‑derived exosomes modulate vascular endothelial injury via miR‑144‑5p/PTEN in intracranial aneurysm.2021 · Hum Cell · Other paper
18. Inflammation and Anti-Inflammatory Targets after Aneurysmal Subarachnoid Hemorrhage.2021 · Int J Mol Sci · Other paper