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Stem cell treatment & Coeliac disease

Checked 2026. nov. 14. · Coeliac disease

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Written based on 16 research studies on PubMed, searched on 2026. nov. 14..

The claim

Posts online say that stem cell treatment helps with coeliac disease.

Where research stands

We found 24 published papers on stem cell treatment and coeliac disease. They were published between 1993 and 2024. 4 of them are studies in people. None of them compared people who got it with a group that did not. None was a study in animals, and 2 were only in cells in the lab. 9 papers are reviews that sum up other studies. 2 research projects on stem cell treatment for coeliac disease are funded and still running.

  • 4In people
  • 0In animals
  • 2Only in the lab

What the studies found

We have not summed up these studies in words yet. The most important papers are listed under Sources.

Verdict

Stem cell treatment has been studied in people with coeliac disease, but not in randomised trials.

What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. Intestinal ex vivo organoid culture reveals altered programmed crypt stem cells in patients with celiac disease.2020 · Sci Rep · Study in people
  2. Treatment response in enteropathy associated T-cell lymphoma; survival in a large multicenter cohort.2015 · Am J Hematol · Study in people
  3. Combination chemotherapy followed by autologous stem cell transplant for enteropathy-associated T cell lymphoma.2007 · Br J Haematol · Study in people
  4. Autologous hematopoietic stem cell transplantation in refractory celiac disease with aberrant T cells.2007 · Blood · Study in people
  5. Mesenchymal stem cells as potential therapeutic approaches in celiac disease.2016 · Gastroenterol Hepatol Bed Bench · Review
  6. Are stem cells a potential therapeutic tool in coeliac disease?2015 · Cell Mol Life Sci · Review
  7. Hematopoietic stem cell transplantation for non-malignant gastrointestinal diseases.2014 · World J Gastroenterol · Review
  8. Intestinal stem cells and celiac disease.2014 · World J Stem Cells · Review
  9. [Future therapeutics in celiac disease].2012 · Harefuah · Review
  10. Enteropathy-associated T-cell lymphoma: epidemiology, clinical features, and current treatment strategies.2011 · Curr Hematol Malig Rep · Review
  11. Circulating hematopoietic stem cells and putative intestinal stem cells in coeliac disease.2015 · J Transl Med · In the lab
  12. Enteric disease in early childhood inhibits microvillus expression by potential stem cells.1993 · Clin Sci (Lond) · In the lab
  13. Correlation between intestinal stem cell niche changes and small bowel crypt failure in patients with treatment-naïve celiac disease.2024 · Indian J Pathol Microbiol · Other paper
  14. A Refractory Celiac Patient Successfully Treated With Mesenchymal Stem Cell Infusions.2016 · Mayo Clin Proc · Other paper
  15. A 37-year-old woman with refractory coeliac disease type II disease treated by stem cell transplantation.2015 · BMJ Case Rep · Other paper
  16. Allogeneic hematopoietic stem cell transplantation may restore gluten tolerance in patients with celiac disease.2013 · J Pediatr Gastroenterol Nutr · Other paper

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