Stem cell treatment & Cytomegalovirus infection

Written based on 26 research studies on PubMed, searched on 2026. nov. 14..

The claim

Posts online say that stem cell treatment helps with cytomegalovirus infection.

Where research stands

We found 281 published papers on stem cell treatment and cytomegalovirus infection. They were published between 1998 and 2026. 9 of them are studies in people. 4 of them compared people who got it with a group that did not. 5 were studies in animals, and 2 were only in cells in the lab. 65 papers are reviews that sum up other studies. 29 new studies in people are running or will start soon, say the trial registers. 7 research projects on stem cell treatment for cytomegalovirus infection are funded and still running.

• 9In people4 with a comparison group
• 5In animals
• 2Only in the lab

What the studies found

We have not summed up these studies in words yet. The most important papers are listed under Sources.

Verdict

Sources

1. Mesenchymal stem cells for the adjunctive treatment of cytomegalovirus pneumonia in hematopoietic stem cell transplant recipients: a Single-center prospective study.2025 · Ann Hematol · Randomised trial
2. Efficacy and safety of extended duration letermovir prophylaxis in recipients of haematopoietic stem-cell transplantation at risk of cytomegalovirus infection: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.2024 · Lancet Haematol · Randomised trial
3. Letermovir for prophylaxis of cytomegalovirus manifestations in adult allogeneic hematopoietic stem cell transplant recipients.2019 · Future Microbiol · Randomised trial
4. Autologous haematopoietic stem cell transplantation: a viable treatment option for CIDP.2014 · J Neurol Neurosurg Psychiatry · Randomised trial
5. CMV-specific T-cell receptor-engineered T-cell therapy as first-line treatment for CMV reactivation after haploidentical hematopoietic stem cell transplantation: a phase 2 trial.2026 · Front Immunol · Study in people
6. Impact of CMV-specific immune reconstitution at the end of letermovir prophylaxis on the development of late cytomegalovirus infection in haematopoietic stem cell transplant recipients (INMUNOEND): a protocol for a prospective, observational, multicentre study.2025 · BMJ Open · Study in people
7. Cytomegalovirus Infection and Treatment in Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Study from a Single Institution in an Endemic Area.2017 · Turk J Haematol · Study in people
8. Cytomegalovirus infection and disease after reduced intensity conditioning allogeneic stem cell transplantation: single-centre experience.2010 · Bone Marrow Transplant · Study in people
9. Reconstitution of lymphocyte populations and cytomegalovirus viremia or disease after allogeneic peripheral blood stem cell transplantation.2003 · J Med Virol · Study in people
10. Treatment of viral retinitis after allogeneic hematopoietic stem cell transplantation with maribavir: A report of three cases and a review of the literature.2026 · Transpl Immunol · Review
11. Cytomegalovirus and cancer stem cells: a hidden alliance in tumor progression and therapy resistance.2026 · Mol Biol Rep · Review
12. Adoptive Virus-Specific T Cell Therapy for Viral Infections After Allogeneic Hematopoietic Stem Cell Transplantation: Current Strategies and Future Perspectives.2026 · Biomolecules · Review
13. Advancing Human Placental Modeling Through Stem-Cell-Derived Trophoblast Organoids and Reprogramming Innovations.2026 · Biomedicines · Review
14. Augmenting immune reconstitution after adult allo-haematopoietic stem cell transplantation: current developments and modifiable determinants.2026 · Curr Opin Hematol · Review
15. [The dual effects of letermovir in allogeneic hematopoietic stem cell transplantation].2026 · Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi · Review
16. Association between anti-thymocyte globulin exposure and clinical outcomes of adult undergoing haploidentical hematopoietic stem cell transplantation with myeloablative conditioning: a pharmacokinetic-guided study.2026 · Transplant Cell Ther · In animals
17. Feasibility and Interim Safety and Efficacy Analysis of a Fast Automated Production of Prophylactic Cytomegalovirus-Specific Cytotoxic T Lymphocytes After Allogeneic Hematopoietic Stem Cell Transplantation.2026 · Transplant Cell Ther · In animals
18. The application of rituximab during the conditioning regimen prevents Epstein - Barr virus infection following rATG-based haploidentical hematopoietic stem cell transplantation in the era of letermovir for cytomegalovirus prophylaxis.2026 · Front Immunol · In animals
19. Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV.2026 · Adv Sci (Weinh) · In animals
20. Efficacy of pp65-specific TCR-T cell therapy in treating cytomegalovirus infection after hematopoietic stem cell transplantation.2022 · Am J Hematol · In animals
21. Tailored conditioning for hematopoietic stem cell transplantation in children with Mendelian susceptibility to mycobacterial disease: A tale of two pathways for IFN-γ and IL-12 defects.2026 · J Hum Immun · In the lab
22. Adoptive cellular therapy for cytomegalovirus infection following allogeneic stem cell transplantation using virus-specific T cells.2008 · Blood Cells Mol Dis · In the lab
23. Deep Phenotyping Reveals Evolution in T cell Phenotype after Hexaviral-specific T cell Infusion Post Hematopoietic Stem Cell Transplant.2026 · Mol Ther · Other paper
24. Endoscopic Findings Can Help Predict Cytomegalovirus Colitis after Hematopoietic Stem Cell Transplantation.2026 · J Anus Rectum Colon · Other paper
25. Divergent CMV and EBV co-infection impact in adult and pediatric hematopoietic stem cell transplantation recipients.2026 · Front Cell Infect Microbiol · Other paper
26. Systemic Medication Adjustment and Short-Term Relapse of Cytomegalovirus Retinitis After Allogeneic Hematopoietic Stem Cell Transplantation: A Research Communication.2026 · Biomedicines · Other paper