Written based on 21 research studies on PubMed, searched on 2026. nov. 14..
The claim
Posts online say that stem cell treatment helps with polycystic ovary syndrome.
Where research stands
We found 84 published papers on stem cell treatment and polycystic ovary syndrome. They were published between 2008 and 2026. 1 of them is a study in people. 1 of them compared people who got it with a group that did not. 36 were studies in animals, and 13 were only in cells in the lab. 15 papers are reviews that sum up other studies. 1 new study in people is running or will start soon, say the trial registers. 1 research project on stem cell treatment for polycystic ovary syndrome is funded and still running.
- 1In people1 with a comparison group
- 36In animals
- 13Only in the lab
What the studies found
We have not summed up these studies in words yet. The most important papers are listed under Sources.
Verdict
Stem cell treatment has been tested in randomised trials in people with polycystic ovary syndrome.
What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- The Effect of Umbilical Cord-Derived Mesenchymal Stem Cells and Secretome on Metabolomic Profiles (C-Peptide, Adiponectin, Fasting Insulin, and Fasting Glucose): A Randomized Controlled Trial.2026 · J Clin Med · Randomised trial
- Mesenchymal stem cells: Guardians of women's health.2024 · Regen Ther · Review
- Advances in Mesenchymal Stem Cell Research Applications for Female Infertility-Mechanisms, Efficacy Parameters, Challenges and Future Roadmap.2024 · Galen Med J · Review
- Application of Mesenchymal Stem Cells in Female Infertility Treatment: Protocols and Preliminary Results.2024 · Life (Basel) · Review
- Induced Pluripotent Stem Cells as a Possible Approach for Exploring the Pathophysiology of Polycystic Ovary Syndrome (PCOS).2024 · Stem Cell Rev Rep · Review
- Therapeutic Potential of Mesenchymal Stem Cells in PCOS.2024 · Curr Stem Cell Res Ther · Review
- Stem cells and exosomes: as biological agents in the diagnosis and treatment of polycystic ovary syndrome (PCOS).2023 · Front Endocrinol (Lausanne) · Review
- Therapeutic Potential of Bone Marrow-Derived Mesenchymal Stem Cells in A Letrozole-Induced Rat Model of Polycystic Ovary Syndrome.2026 · Int J Fertil Steril · In animals
- Mesenchymal stem cells reverse ovarian dysfunction by inhibiting autophagy in polycystic ovary syndrome mice.2026 · Stem Cell Res Ther · In animals
- Therapeutic Effects of Adipose-Derived Mesenchymal Stem Cell Exosome like Nanovesicles on Granulosa Cell Function in a Mouse Model of Polycystic Ovarian Syndrome: Involvement of FOXO3, Map1lc3b, SF-1 Genes.2026 · Reprod Sci · In animals
- Adiponectin preserves follicles through ADIPOR1/ADIPOR2-driven fatty acid metabolism.2026 · Mol Metab · In animals
- Therapeutic potential of adipose-derived mesenchymal stem/stromal cells conditioned medium versus adipose-derived mesenchymal stem/stromal cells on treatment of polycystic ovary In-vivo.2026 · Tissue Cell · In animals
- Therapeutic Potential of Mesenchymal Stem Cells Transplantation in Nonalcoholic Fatty Liver Disease of Polycystic Ovary Syndrome: A Cross-Talk Between Ovary and Liver.2026 · J Obstet Gynaecol Res · In animals
- Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient.2025 · Stem Cell Res · In the lab
- The Effect of Normal Follicular Fluid on the Differentiation of PCOS Ovarian Stem Cells into Oocyte-Like Cells.2023 · Adv Biomed Res · In the lab
- Generation of an induced pluripotent stem cell line AMUFAHi002-A from polycystic ovary syndrome patient.2022 · Stem Cell Res · In the lab
- Mesenchymal Stem Cell-Conditioned Media Regulate Steroidogenesis and Inhibit Androgen Secretion in a PCOS Cell Model via BMP-2.2021 · Int J Mol Sci · In the lab
- Recent trends in polycystic ovary syndrome treatment based on adult stem cell therapies.2025 · Clin Exp Reprod Med · Other paper
- Role of Menstrual Blood Stem Cell-Derived Secretome, Follicular Fluid, and Melatonin in Oocyte Maturation and Embryo Development in Polycystic Ovary Syndrome.2025 · Curr Stem Cell Res Ther · Other paper
- Complete lasting reversal of polycystic ovary syndrome from intravenous umbilical cord derived mesenchymal stem cell infusion.2024 · Am J Stem Cells · Other paper
- Polycystic ovary syndrome: emerging stem cell therapies.2024 · Rev Assoc Med Bras (1992) · Other paper
