Célpont

AR

Androgen receptor

Más néven: androgen receptor

16nyitott vizsgálat
38vizsgálat összesen
287publikáció
0kutató

Betegségek

Prostate cancer26 vizsgálat
Triple-negative breast cancer7 vizsgálat
Metastatic breast cancer5 vizsgálat
High blood pressure2 vizsgálat
Ovarian cancer2 vizsgálat

Az elmúlt 24 hónap

Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.

VizsgálatokPublikációkPreprintekPályázatok

Publikáció
Estrogen-related receptor γ functions as a novel corepressor of androgen receptor by destabilizing receptor conformation and blocking coactivator recruitment.
2026. nov. 2.· Journal of biochemistry· PUBMED
Publikáció
Eupalinolide B targets the USP10-AR-MTHFD1 axis to sensitize castration-resistant prostate cancer to enzalutamide.
2026. okt. 23.· Phytomedicine : international journal of phytotherapy and phytopharmacology· PUBMED
Publikáció
ERG inhibition selectively sensitizes ERG-positive prostate cancer to radiation through DNA repair vulnerabilities and enhances response to androgen receptor inhibitors.
2026. okt. 23.· Journal of experimental & clinical cancer research : CR· PUBMED
Publikáció
Beyond pairwise comparisons of androgen receptor signaling inhibitors in nonmetastatic castration-resistant prostate cancer.
2026. okt. 12.· ESMO real world data and digital oncology· PUBMED
Vizsgálat
A clinical trial to learn about the effects of INR731 alone or with an androgen receptor pathway inhibitor (ARPI) in men with prostate cancer
2026. okt. 8.· PHASE1 · RECRUITING· CTIS
Publikáció
Retraction notice to "A cross-talk between the androgen receptor and the epidermal growth factor receptor leads to p38MAPK-dependent activation of mTOR and cyclinD1 expression in prostate and lung cancer cells" [Int. J. Biochem. Cell Biol. 41 (3) (2009) 603-614].
2026. okt. 7.· The international journal of biochemistry & cell biology· PUBMED
Publikáció
A novel multiplex digital PCR assay for simultaneous quantification of androgen receptor amplification, mutations, and splice variants in cell-free nucleic acids from metastatic castration-resistant prostate cancer.
2026. okt. 6.· The journal of liquid biopsy· PUBMED
Vizsgálat
A Prospective Study Based on Spatial Multi-omics to Predict the Efficacy of ADT Combined With Second-generation Novel Hormonal Agents in Metastatic Hormone-sensitive Prostate Cancer.
2026. okt. 1.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Vizsgálat
Clinical Trial to Test Efficacy of Targeting Hypoxia Combined With ARSI After First-line ARSI Therapy for Castrate Resistant Prostate Cancer
2026. okt. 1.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publikáció
β1-AR Autoantibody-Mediated Expansion of Cardiotoxic CD4+CD28- T Cells Contributes to the Progression of Heart Failure.
2026. okt. 1.· JACC. Basic to translational science· PUBMED
Publikáció
TRPML1 inhibitor ML-SI1 suppresses prostate cancer through dual regulation of androgen receptor and polyamine metabolism.
2026. szept. 28.· Frontiers in medicine· PUBMED
Publikáció
Immunohistochemical evaluation of androgen receptor expression in endometrial carcinoma and its clinicopathological significance.
2026. szept. 26.· Diagnostic pathology· PUBMED
Publikáció
Erratum: CYP19A1 is downregulated by BRD4 and suppresses castration-resistant prostate cancer cell invasion and proliferation by decreasing AR expression.
2026. szept. 25.· American journal of cancer research· PUBMED
Preprint
AR-V7 Utilizes a Noncanonical Nuclear Localization Signal to Sustain Androgen-Independent Nuclear Import and Signaling.
2026. szept. 24.· bioRxiv : the preprint server for biology· PUBMED
Publikáció
Dysregulation of neuronal androgen receptor signaling by divergent collaborative transcription factors in Alzheimer's disease.
2026. szept. 22.· iScience· PUBMED
Publikáció
The AR/ARD1/DLGAP5 axis drives oncogenesis and immune evasion via PD-L1 upregulation in androgen receptor-positive triple-negative breast cancer.
2026. szept. 16.· Translational research : the journal of laboratory and clinical medicine· PUBMED
Publikáció
Developing a Fluorescence-Based High-Throughput Screening Method for Natural Product Fractions to Identify Inhibitors of AR-V7 for Castration-Resistant Prostate Cancer.
2026. szept. 15.· Pharmaceutics· PUBMED
Publikáció
Detection of androgen receptor (AR) splice variants across diverse prostatic and non-prostatic tumor types using the TruSight Oncology 500 (TSO500) assay.
2026. szept. 11.· Human pathology· PUBMED
Publikáció
AR/PARP Dual-Targeting Bioactive Photosensitizer for Photo-Immunotherapy of Prostate Cancer.
2026. szept. 9.· Advanced materials (Deerfield Beach, Fla.)· PUBMED
Publikáció
Biochanin A inhibits the activity of androgen receptor mutants to suppress the development of prostate cancer.
2026. szept. 1.· Asian journal of andrology· PUBMED
Publikáció
Comment on: "Deciphering the role of zingiber officinale phytochemicals for the treatment of prostate cancer: Interactions of phytochemicals with androgen receptor prostate cancer mutant H874Y ligand binding domain"-A call to validate AR signaling modulation in H874Y-expressing prostate cancer cells.
2026. szept. 1.· Urologic oncology· PUBMED
Publikáció
Sanguinarine chloride exerts its antitumor effects on enzalutamide-resistant prostate cancer by inhibiting cell proliferation and promoting senescence via targeting AR signaling.
2026. aug. 30.· Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico· PUBMED
Publikáció
Darolutamide-based triplet therapy versus androgen receptor pathway inhibitor-based doublet therapy for metastatic castration-sensitive prostate cancer: a real-world analysis using the TriNetX database.
2026. aug. 28.· Japanese journal of clinical oncology· PUBMED
Publikáció
Erratum: The RNA helicase DDX17 enhances androgen receptor stability by interacting with the E3 ubiquitin ligase SPOP in prostate cancer.
2026. aug. 27.· Translational andrology and urology· PUBMED
Publikáció
Neutropenia events with androgen receptor pathway inhibitor-containing versus control therapies in prostate cancer patients: a systematic review and meta-analysis.
2026. aug. 22.· BMC cancer· PUBMED
Publikáció
Cotinine enhances androgen receptor stability and promotes androgen-dependent proliferation in prostate cancer cells: An in vitro study.
2026. aug. 19.· Archives of biochemistry and biophysics· PUBMED
Vizsgálat
Study of Oral MRT-2359 With Apalutamide in Prostate Cancer
2026. aug. 18.· PHASE2 · RECRUITING· CTGOV
Publikáció
Prognostic Value of Androgen Receptor (AR) Gene Alterations Detected in Circulating Tumor DNA (ctDNA) in Patients With Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Meta-analysis.
2026. aug. 18.· Clinical genitourinary cancer· PUBMED
Publikáció
Effect of BMI on efficacy of androgen receptor pathway inhibitors in patients with metastatic hormone-sensitive prostate cancer.
2026. aug. 18.· Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners· PUBMED
Publikáció
Utilization patterns of second-generation androgen receptor pathway inhibitors as first-line therapy for prostate cancer in the United States.
2026. aug. 14.· Prostate cancer and prostatic diseases· PUBMED

Ki dolgozik rajta

Kutatók, akik publikáltak erről a célpontról. Hagyd ki a saját társszerzői körödet, hogy olyanokat találj, akiket még nem ismersz.

Ezen a célponton még nincs nyilvános kutatói profil.

Rögzített célpontnév-listát keresünk a címekben, a kulcsszavakban, a beavatkozások nevében és a MeSH-kifejezésekben. Az említés nem bizonyítja, hogy a munka valóban arra a célpontra irányul.

Hibát jelzek