Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
Quantitative systems pharmacology modeling identifies synthetic lethality opportunities with DNA damage response inhibitors in ATM-deficient chronic lymphocytic leukemia - a computational simulation study.
2026. nov. 3.· Journal of pharmacokinetics and pharmacodynamics· PUBMED
Publikáció
Methylmalonic Acid Induces Oxaliplatin Resistance Through Promoting DNA Damage Repair via the ATM/ATR Pathway in Gastric Cancer.
2026. okt. 15.· FASEB journal : official publication of the Federation of American Societies for Experimental Biology· PUBMED
Publikáció
Retraction Note: In silico and in vitro assessment of TP53, ATM, RAD51, and BAX genes in gastric cancer and their contribution to radiotherapy resistance.
2026. okt. 10.· Hereditas· PUBMED
Preprint
Combined HDAC and ATM inhibition with radiation in preclinical glioblastoma models.
2026. okt. 7.· bioRxiv : the preprint server for biology· PUBMED
Publikáció
ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review.
2026. szept. 25.· Medical oncology (Northwood, London, England)· PUBMED
Publikáció
A rare ATM variant in a Colombian family with chorea-ataxia syndrome: implications for an early diagnosis.
2026. szept. 24.· Neurogenetics· PUBMED
Publikáció
Fermented wheat germ extract modulates organic selenium availability to regulate programmed cell death and metabolic reprogramming through the ATM/ATR/p53 pathway.
2026. szept. 23.· Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)· PUBMED
Publikáció
ATM inhibition attenuates ferroptosis-associated injury and reduces infarct volume in experimental stroke.
2026. szept. 22.· Ferroptosis and oxidative stress· PUBMED
Publikáció
The ATM inhibitor KU55933 inhibits TGF-β1-mediated epithelial to mesenchymal transition in colorectal cancer cells.
2026. szept. 21.· Frontiers in oncology· PUBMED
Publikáció
Inhibition of ATM, ATR and DNA-PK radiosensitises 3D uveal melanoma models to X-rays and proton beam therapy.
2026. aug. 14.· Frontiers in oncology· PUBMED
Publikáció
Nuclear SOD1 links ATM-CHK2 signaling to ADH5/GSNOR transcription in SHSY-5Y SOD1G93A cellular models of ALS.
2026. aug. 12.· Nitric oxide : biology and chemistry· PUBMED
Publikáció
Epigenetic LOCK chromatin links H3K9 modifications to ATM-γH2AX signaling in HIV-Tat and opioid neuroinflammation.
2026. aug. 5.· Cell death & disease· PUBMED
Publikáció
MPT0E028, a pan-HDAC inhibitor, ameliorates bleomycin-induced pulmonary fibrosis by promoting AT2-to-AT1 differentiation through the ATM/AMPK/FoxO1 pathway.
2026. júl. 21.· Journal of biomedical science· PUBMED
Publikáció
ATM Deficiency Induces TGFβ-Mediated Stromal Programming in Pancreatic Cancer.
2026. júl. 15.· Cancer research· PUBMED
Publikáció
Pemetrexed potentiates γδ T cell-based immunotherapy in NSCLC through ATM-STING-NF-κB-mediated induction of NKG2D ligands.
2026. júl. 14.· International immunopharmacology· PUBMED
Publikáció
Cancer-related microangiopathic hemolytic anemia (CR-MAHA) in a metastatic breast cancer patient with a germ-line ATM single nucleotide variant and an ESR1 fusion variant: insights from a case report on early diagnosis and improved outcomes.
2026. júl. 7.· Frontiers in oncology· PUBMED
Publikáció
Ceralasertib Monotherapy in Patients with ATM-Altered Advanced Solid Tumors or Metastatic Castration-Resistant Prostate Cancer: Data from the Phase IIa PLANETTE Study.
2026. júl. 1.· Cancer research communications· PUBMED
Vizsgálat
Human ADME Study of [14C]-AZD1390
2026. jún. 30.· PHASE1 · NOT_YET_RECRUITING· CTGOV
Publikáció
ATM c.7374_7375insAlu is a French-Canadian founder pathogenic variant associated with predisposition to pancreatic and breast cancer.
2026. jún. 25.· Journal of medical genetics· PUBMED
Publikáció
Suppression of ATM kinase signaling accelerates cellular senescence.
2026. jún. 11.· Stem cell reports· PUBMED
Publikáció
Impact of ataxia-telangiectasia mutated (ATM) loss on radiobiological and immune response to radium-223 in prostate cancer in vitro models.
2026. máj. 30.· Clinical and translational radiation oncology· PUBMED
Publikáció
Reply to the letter of editor addressed by Thulamy Raman D. Et al., about our article entitled "Radiosensitivity and delayed radiation-induced Nucleo-shuttling of the ATM protein in fibroblasts from Duchenne muscular dystrophy expressing residual dystrophin".
2026. máj. 23.· Journal of the neurological sciences· PUBMED
Publikáció
Comment on "Radiosensitivity and delayed radiation-induced nucleo-shuttling of the ATM protein in fibroblasts from Duchenne muscular dystrophy expressing residual dystrophin".
2026. máj. 22.· Journal of the neurological sciences· PUBMED
Publikáció
ATR inhibition in combination with hypofractionated radiotherapy is superior to ATM inhibition with regard to ex vivo CD8 + T cell activation particularly for HPV-negative head and neck cancer cells.
2026. máj. 19.· Oral oncology· PUBMED
Preprint
Ablation of glypican-3 enhances radiosensitivity in liver cancer by prolonging G2/M arrest and activating the ATM/CHK2 pathway.
2026. máj. 14.· bioRxiv : the preprint server for biology· PUBMED
Publikáció
The Mechanism of Mg2+-Mediated Inhibition of Cervical Cancer by Inducing a Senescence-like State via the ATM/CHK2/p21 Signaling Pathway.
2026. máj. 14.· International journal of molecular sciences· PUBMED
Publikáció
Comment on "Radiosensitivity and delayed radiation-induced nucleo-shuttling of the ATM protein in fibroblasts from Duchenne muscular dystrophy expressing residual dystrophin".
2026. máj. 7.· Journal of the neurological sciences· PUBMED
Publikáció
PARG inhibition in ATM-deficient prostate cancer: from mechanistic discovery to therapeutic potential.
2026. máj. 6.· Journal of translational medicine· PUBMED
Publikáció
Reply to the Letter of Editor addressed by D.M. Sati et al., about our article entitled "Radiosensitivity and Delayed Radiation-Induced Nucleo-shuttling of the ATM Protein in Fibroblasts from Duchenne Muscular Dystrophy Expressing Residual Dystrophin".
2026. máj. 5.· Journal of the neurological sciences· PUBMED
Publikáció
A Phase II Trial of Niraparib in Patients with Advanced Pancreatic Cancer Harboring Pathogenic Variants in ATM, BRCA1, BRCA2, PALB2, and CHEK2.
2026. máj. 1.· Clinical cancer research : an official journal of the American Association for Cancer Research· PUBMED