Amiotrófiás laterálszklerózis (ALS): ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• TDP-43 8
• SOD1 8
• C9orf72 4
• NRF2 0
• STING 0
• SIRT1 0
• HDAC 0
• NLRP3 0
• TREM2 0
• BDNF 0
• MAPK 0
• APOE 0
• GLP-1 0
• HMGB1 0
• mTOR 0
• SMN1 0
• TP53 0
• AMPK 0
• BTK 1
• CXCR4 0
• HSP90 1
• JAK 0
• JNK 0
• LAG-3 0
• NMDA 0
• PI3K 0
• PINK1 0
• PPAR 0
• TFEB 0
• TNF 0
• AKT 0
• APP 0
• ATM 0
• AXL 0
• BCL-2 0
• CDK4/6 0
• COX-2 0
• CSF1R 0
• ERK 0
• GPX4 0
• IL-1 0
• MAPT 0
• PARP 0
• PCSK9 0
• PDE4 1
• PSEN1 0
• PTEN 0
• SNCA 0
• STK11 0
• TLR4 0
• TTR 0
• VEGF 0
• YAP 0

1+ intézményből 1, a friss publikációk és a nyitott vizsgálatok szerint rendezve. Ez nem minőségi rangsor.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• NIH NINDS · F31

  Uncovering the Role of Perisynaptic Schwann Cells in C9ORF72 Amyotrophic Lateral Sclerosis Susceptibility and Progression

  University of Chicago· Chicago, Egyesült Államok· 50 114 USD awarded in fiscal year 2026· until 2029. szept.

• NIH NCI · F31

  Deciphering RNA Zipcodes: A Novel Framework for Subcellular Localization Element Annotation

  Baylor College of Medicine· Houston, Egyesült Államok· 50 114 USD awarded in fiscal year 2026· until 2029. szept.

• NIH NINDS · F31

  Nuclear-cytoskeletal coupling through the giant KASH protein ANC-1 maintains neuronal mechanical integrity during aging

  University of California at Davis· Davis, Egyesült Államok· 43 471 USD awarded in fiscal year 2026· until 2028. nov.

• NIH NIDCD · F31

  An articulatory brain-computer interface approach for restoring expressive communication to people with paralysis

  University of California at Davis· Davis, Egyesült Államok· 43 752 USD awarded in fiscal year 2026· until 2029. szept.

• NIH NINDS · R56

  Unraveling Mechanisms Governing Cell Clearance Deficits in C9ORF72-ALS/FTD

  University of Missouri-Columbia· Columbia, Egyesült Államok· 539 427 USD awarded in fiscal year 2026· until 2027. aug.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Curation, Integration, Modelling and Rational Design of Small Molecule Amyloid Inhibitors (AmyStoppers)

  Vilniaus Universitetas· Vilnius, Litvánia· EU contribution 196 976 EUR· until 2029. márc.

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-SE

  From Stool to Solutions: Diagnose, Decode, Disruptors, and Deliver Interventions for the Human Gut Microbiota in Neurodegenerative Diseases. (GUT-4D)

  Universita Degli Studi del Piemonte Orientale Amedeo Avogadro· Vercelli, Olaszország· EU contribution 1 568 130 EUR· until 2030. szept.· 8 countries

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Unraveling the impact of RNA-editing in neurodegeneration: a focus on TDP-43 related frontotemporal dementia. (NeuroEDIT)

  Asociacion Instituto de Investigacion Sanitaria Biogipuzkoa· Donostia-San Sebastian, Spanyolország· EU contribution 194 075 EUR· until 2028. aug.· 2 countries

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  POLYMND: Polyamine dysregulation in Motor Neuron Disease as a targetable driver of astrocyte–neuron dysfunction

  The Chancellor Masters and Scholars of the University of Cambridge· Cambridge, Egyesült Királyság· EU contribution 276 188 EUR· until 2028. aug.

• European Commission (Horizon Europe) · HORIZON-ERC

  Engineered Humanized Spinal Cord Construct for Advancing Health and Disease Research (SpineCraft)

  Fundacio Institut de Bioenginyeria de Catalunya· Barcelona, Spanyolország· EU contribution 2 743 700 EUR· until 2031. márc.

  The disease is named only in the funder's project summary, not in the title.

10 of 510 running projects, newest first. Listed amounts together: 399,2 M USD + 25,3 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

Ebben a nézetben egy vizsgálat sem jelzi, hogy megosztaná a résztvevői adatokat.

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 7
• Organoids 7
• Mendelian Randomization Analysis 18
• CRISPR-Cas Systems 8
• Gene Expression Profiling 24
• Sequence Analysis, RNA 2
• Whole Genome Sequencing 6
• Exome Sequencing 6
• Proteomics 29
• Metabolomics 7
• Mass Spectrometry 6
• Flow Cytometry 2
• Immunohistochemistry 5
• Liquid Biopsy 2
• Positron-Emission Tomography 14
• Magnetic Resonance Imaging 57
• Machine Learning 18
• Deep Learning 7
• Cohort Studies 81
• Genome-Wide Association Study 24

• Mapping high resolution, multidimensional phase diagrams of near-physiological protein condensates.

  Nat Commun, 2026. szept.

• Identifying candidate therapeutic targets in amyotrophic lateral sclerosis through a transcriptome-wide machine-learning consensus approach for drug repurposing.

  Neuroscience, 2026. aug.

• Identification of Glycolysis-Related Diagnostic Biomarkers for Amyotrophic Lateral Sclerosis Using Machine Learning.

  Clin Lab, 2026. aug.

• Identification of Reliable Biomarkers for ALS Through Machine Learning Approach.

  Stud Health Technol Inform, 2026. máj.

• WBT-DC pipeline: a cross-cohort and cross-platform disease classification pipeline based on whole-blood transcriptomics.

  J Transl Med, 2026. máj.

• Unveiling an ALS Blood Transcriptomic Signature: A Machine Learning Classifier Distinct from Neurodegenerative Controls.

  Neuroinformatics, 2026. ápr.

• Smart Sensor-Driven Gait Rehabilitation Walker Using Machine Learning for Predictive Home-Based Therapy.

  Sensors (Basel), 2026. ápr.

• Physiological predictors of respiratory motor plasticity: A machine-learning reappraisal of phrenic motor facilitation.

  Respir Physiol Neurobiol, 2026. ápr.

• Development of a machine learning-based survival prediction model for ALS inclusive of the advanced-stage population.

  Amyotroph Lateral Scler Frontotemporal Degener, 2026. ápr.

• Exploring the feasibility of near-infrared spectroscopy and machine learning for detecting cardiovascular diseases and diabetes mellitus in fingernails.

  Analyst, 2026. márc.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.