Crohn-betegség: ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• TNF 7
• IL-23 10
• JAK 0
• NLRP3 0
• IL-1 0
• GLP-1 0
• LRRK2 0
• IL-17 0
• IL-6 0
• MAPK 0
• PPAR 0
• CD19 3
• JNK 0
• STAT3 0
• TLR4 0
• TP53 0
• AKT 0
• AMPK 0
• BCMA 2
• CCR5 0
• IL-4 0
• NRF2 0
• SIRT1 0
• STING 0
• YAP 0
• ACE2 0
• AXL 0
• BRD4 0
• CD30 0
• CD40 0
• CD47 0
• COX-2 0
• CTLA-4 0
• DPP-4 0
• FTO 0
• G6PD 0
• GIP 0
• GPX4 0
• HDAC 1
• HIF-1 0
• HMGB1 0
• IL-13 0
• IL-15 1
• KMT2A 0
• MMP-9 0
• mTOR 0
• MUC1 0
• PARP 0
• PD-1 0
• PD-L1 0
• PDE4 0
• PI3K 0
• PINK1 0
• RAS 0
• RUNX1 0
• TFEB 0
• TYK2 0

4+ intézményből 4, a friss publikációk és a nyitott vizsgálatok szerint rendezve. Ez nem minőségi rangsor.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• NIH NIDDK · R01

  Stem- and Paneth cell-specific CD74 functions control gut immune responses

  Rutgers Biomedical and Health Sciences· Newark, Egyesült Államok· 780 495 USD awarded in fiscal year 2026· until 2030. jún.

• NIH NIDDK · SB1

  Development of TP-317 for Ulcerative Colitis

  Thetis Pharmaceuticals, Llc· Deep River, Egyesült Államok· 669 925 USD awarded in fiscal year 2026· until 2028. júl.

• NIH NIDDK · R01

  Identification of bacterial derived proteases that inhibit inflammation and pain signaling in the gut

  Stanford University· Stanford, Egyesült Államok· 3 802 100 USD awarded in fiscal year 2026· until 2030. aug.

• NIH NIDDK · R44

  An allogeneic and gut specific Engineered T regulatory cell therapy for the treatment of Inflammatory Bowel Disease

  Gentibio, Inc.· Cambridge, Egyesült Államok· 1 061 227 USD awarded in fiscal year 2026· until 2028. aug.

• NIH NIDDK · R01

  Per- and poly-fluoroalkyl substances (PFAS) exposure and glycosylation alterations preceding inflammatory bowel disease

  Icahn School of Medicine at Mount Sinai· New York, Egyesült Államok· 698 943 USD awarded in fiscal year 2026· until 2031. júl.

• European Commission (Horizon Europe) · HORIZON-RIA

  Secretome bAsed Therapy for complex perianal fistUlas in CRohN’s disease (SATURN)

  Everzom· Paris, Franciaország· EU contribution 13 286 449 EUR· until 2031. szept.· 5 countries

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Characterising the molecular and cellular basis of enteric nervous system alterations in the inflamed gut (NeurogENSity)

  Karolinska Institutet· Stockholm, Svédország· EU contribution 206 888 EUR· until 2027. aug.

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC-POC

  A Fibroblast-Targeting Advanced Lead Mitigating Inflammation and Fibrosis in IBD (FIBROLEAD)

  Inolysis Monoprosopi Idiotiki Kefalaiouchiki Etaireia· Melissia Athens, Görögország· EU contribution 150 000 EUR· until 2027. jan.

• European Commission (Horizon Europe) · HORIZON-ERC-POC

  RNA Epithelial Approach for Crohn’s Treatment (RE-ACT)

  Medical Research Infrastructure Development and Health Services Fund By the Sheba Medical Center· Ramat Gan, Izrael· EU contribution 150 000 EUR· until 2026. nov.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-GF

  Unravelling neuroimmune crosstalk to find novel treatment targets for inflammatory bowel disease (UNTANGLED)

  Stichting Amsterdam Umc· Amsterdam, Hollandia· EU contribution 432 468 EUR· until 2028. ápr.· 2 countries

10 of 295 running projects, newest first. Listed amounts together: 145,7 M USD + 63,7 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Leállított, visszavont és felfüggesztett vizsgálatok, a szponzor által a regiszterben megadott okkal, szó szerint idézve.

• Visszavonták

  A Study on Infections in Adults With Ulcerative Colitis/Crohn's Disease

  NCT07250815· Takeda· Frissítve: 2026. okt. 15.

  “Sponsor decision”A regiszter szövege, változtatás nélkül. Forrás

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

• A Study on Infections in Adults With Ulcerative Colitis/Crohn's Disease

  NCT07250815· Takeda· Forrás

• Assessing the Drug Exposure Risk of Infants Breastfed by Women With Inflammatory Bowel Disease

  NCT03397108· The Hospital for Sick Children· Forrás

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 22
• Organoids 13
• Mendelian Randomization Analysis 44
• Gene Expression Profiling 48
• Sequence Analysis, RNA 6
• Exome Sequencing 4
• Proteomics 14
• Metabolomics 23
• Mass Spectrometry 5
• Flow Cytometry 6
• Immunohistochemistry 9
• Positron-Emission Tomography 3
• Magnetic Resonance Imaging 76
• Machine Learning 36
• Deep Learning 13
• Cohort Studies 97
• Genome-Wide Association Study 58

• Multi-modal ensemble learning prediction of anti-TNF treatment response in pediatric patients with Crohn's disease using clinical, radiomic, and deep learning MR enterography features.

  Inflamm Bowel Dis, 2026. okt.

• Histological aging signatures for monitoring tissue-specific aging and disease.

  Nat Med, 2026. aug.

• A novel deep learning network for small bowel ulcerative lesion detection and differential diagnosis on double-balloon endoscopy images.

  Biomed Phys Eng Express, 2026. jún.

• IBDome: An Integrated Molecular, Histopathological, and Clinical Atlas of Inflammatory Bowel Diseases.

  Gastroenterology, 2026. jún.

• Deep learning layer-specific collagen quantification correlates with activity and is associated with outcomes in Crohn's disease.

  J Crohns Colitis, 2026. jún.

• Deep learning-based quantitative histopathology of endoscopic biopsies in Crohn's disease: a retrospective cross-sectional validation study.

  Front Immunol, 2026. jún.

• STAID: A Self-Refining Deep Learning Framework for Spatial Cell-Type Deconvolution with Biologically Informed Modeling.

  Adv Sci (Weinh), 2026. máj.

• Deep Learning-Driven Analysis and Quantification of Histopathologic Features in a Dextran Sulfate Sodium-Induced Colitis Mouse Model.

  Am J Pathol, 2026. máj.

• Artificial intelligence and capsule endoscopy.

  Rev Esp Enferm Dig, 2026. máj.

• INTELCAPE: A Deep Learning-Powered System for Automated, High-Accuracy Crohn's Disease Diagnosis via Capsule Endoscopy.

  Clin Gastroenterol Hepatol, 2026. márc.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.