IgA-nefropátia: ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• BCMA 7
• CD19 8
• SGLT2 1
• CD20 0
• CD38 0
• IL-6 0
• JAK 0
• NLRP3 0
• TLR4 0
• mTOR 0
• STING 0
• IL-17 0
• AKT 0
• AMPK 0
• EGFR 0
• FAK 0
• GPX4 0
• HER2 0
• IL-1 0
• MET 0
• MYC 0
• NRF2 0
• PD-1 0
• PI3K 0
• STAT3 0
• TP53 0

1+ intézményből 1, a friss publikációk és a nyitott vizsgálatok szerint rendezve. Ez nem minőségi rangsor.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• NIH NIDDK · R01

  Determination of structural features critical for nephritogenic properties of IgA1-containing immune complexes in IgA nephropathy

  University of Alabama at Birmingham· Birmingham, Egyesült Államok· 743 278 USD awarded in fiscal year 2026· until 2030. máj.

• NIH NIDDK · R01

  Dapagliflozin in Active Lupus Nephritis: A Pilot and Feasibility Randomized Trial

  Brigham and Women's Hospital· Boston, Egyesült Államok· 364 560 USD awarded in fiscal year 2026· until 2028. dec.

• NIH NIDDK · F32

  The Impact of APOL1 Copy Number Variation on Kidney Disease Susceptibility in African Americans

  Beth Israel Deaconess Medical Center· Boston, Egyesült Államok· 79 348 USD awarded in fiscal year 2026· until 2027. aug.

• NIH NIDDK · R01

  Interrogating The Biology Of Human Lupus Nephritis Using Single Cell Resolution Spatial Transcriptomics

  Seattle Children's Hospital· Seattle, Egyesült Államok· 801 241 USD awarded in fiscal year 2026· until 2028. jan.

• NIH NIAID · R01

  Contributions of autophagy-related genes in lupus

  Oklahoma Medical Research Foundation· Oklahoma City, Egyesült Államok· 751 755 USD awarded in fiscal year 2026· until 2027. júl.

• European Commission (Horizon Europe) · HORIZON-ERC

  Role of CD1c-reactive T cells and lipid antigens in post-streptococcal disease (CReativeLipid)

  The Chancellor, Masters and Scholars of the University of Oxford· Oxford, Egyesült Királyság· EU contribution 1 491 316 EUR· until 2030. szept.

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC

  Antigen-specific treatments to target autoimmune kidney diseases (AUTO-TARGET)

  Universitaetsklinikum Hamburg-Eppendorf· Hamburg, Németország· EU contribution 1 499 663 EUR· until 2030. márc.

• European Commission (Horizon Europe) · HORIZON-RIA

  Gene-edited T cells combating IgA Nephropathy. A blueprint approach for safe & efficient genome editing of T cells to sustainably combat several immune diseases and cancers related to B-cell pathology (geneTIGA)

  Charite - Universitaetsmedizin Berlin· Berlin, Németország· EU contribution 6 393 734 EUR· until 2026. dec.· 8 countries

8 of 22 running projects, newest first. Listed amounts together: 11,1 M USD + 9,4 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

• A Study to Investigate Safety and Effect of Sparsentan in Combination With SGLT2 Inhibition in Participants With IgAN

  NCT05856760· Travere Therapeutics, Inc.· Forrás

• Multicentre Clinical Study to Evaluate the Effect of Personalized Therapy on Patients With Immunoglobulin A Nephropathy.

  NCT04662723· Fondazione Schena· Forrás

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 6
• Mendelian Randomization Analysis 14
• Gene Expression Profiling 14
• Proteomics 8
• Metabolomics 5
• Flow Cytometry 2
• Immunohistochemistry 4
• Magnetic Resonance Imaging 1
• Machine Learning 9
• Deep Learning 3
• Cohort Studies 14
• Genome-Wide Association Study 20

• Identification of key genes related to arginine metabolism in immunoglobulin A nephropathy through the combination of scRNA-seq and bulk RNA-seq data.

  Front Immunol, 2026. aug.

• Combination scRNA-seq with GWAS identifies genetic risk factors in IgA nephropathy: An observational study.

  Medicine (Baltimore), 2026. máj.

• ACSL4 mediates ferroptosis to promote immunoglobulin A nephropathy progression: scRNA-seq analysis.

  Sci Rep, 2026. márc.

• Integrated analysis of single-cell and bulk RNA-seq data identifies NR4A1-associated macrophages in immunoglobulin A nephropathy.

  Colloids Surf B Biointerfaces, 2025. dec.

• Single-cell analysis reveals shared adaptive responses across different types of podocyte injury.

  Front Immunol, 2025. dec.

• Single-cell transcriptomic analysis reveals T cell heterogeneity and metabolic reprogramming in human immune-mediated glomerulonephritis.

  Autoimmunity, 2025. nov.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.