Osteoarthritis: ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• PI3K 0
• NRF2 0
• NLRP3 0
• MAPK 0
• AMPK 1
• GLP-1 3
• IL-1 1
• AKT 0
• mTOR 0
• STAT3 0
• SIRT1 0
• TLR4 0
• JAK 0
• COX-2 0
• ERK 0
• CTNNB1 0
• IL-6 0
• PPAR 0
• STING 0
• TP53 0
• GPX4 0
• HIF-1 0
• JNK 0
• TNF 0
• YAP 0
• PINK1 0
• PTEN 0
• VEGF 0
• IL-17 0
• METTL3 0
• RANKL 0
• EGFR 0
• BCL-2 0
• CXCR4 0
• FTO 0
• HMGB1 0
• MMP-9 0
• SGLT2 1
• CGRP 0
• FGFR 0
• HDAC 0
• KEAP1 0
• MDM2 0
• PARP 0
• APOE 0
• BRD4 0
• CDK4/6 0
• ESR1 0
• FAK 0
• GIP 0
• HER2 0
• HSP90 0
• MEK 0
• NMDA 0
• TREM2 0
• APP 0
• AR 0
• ARID1A 0
• CD47 0
• CFTR 0

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• NIH NIA · F30

  Dissecting Age-related Changes in Stem Cell-based Bone-Gut Crosstalk

  University of California at Davis· Davis, Egyesült Államok· 43 752 USD awarded in fiscal year 2026· until 2029. szept.

• NIH NINDS · R43

  Development of an Anti-Nerve Growth Factor Active Immunotherapy for Difficult-to-Manage Pain

  Twilight Bioscience, Inc.· Topsfield, Egyesült Államok· 350 188 USD awarded in fiscal year 2026· until 2028. aug.

• NIH NIAMS · R56

  Understanding the Roles of Synovitis, Knee-Adjacent Obesity and Sarcopenia in Pain Phenotypes and Structural Progression of Knee Osteoarthritis - An Analysis of the Entire Osteoarthritis Initiative

  University of California, San Francisco· San Francisco, Egyesült Államok· 620 656 USD awarded in fiscal year 2026· until 2027. aug.

• NIH NIAMS · R01

  Fe Metabolism Compromises Articular Chondrocytes during Joint Degeneration

  University of Iowa· Iowa City, Egyesült Államok· 660 873 USD awarded in fiscal year 2026· until 2031. aug.

• NIH NIDCR · R43

  SN102: a Novel Gene Therapy for Trigeminal Neuralgia Pain

  Sereneuro Therapeutics, Inc.· Baltimore, Egyesült Államok· 338 115 USD awarded in fiscal year 2026· until 2027. szept.

• European Commission (Horizon Europe) · HORIZON-ERC

  Biofabrication of gene activated grafts targeting synovial joint inflammation and meniscus repair (SMART-MENISCUS)

  The Provost, Fellows, Foundation Scholars & the Other Members of Board, of the College of the Holy & Undivided Trinity of Queen Elizabeth Near Dublin· Dublin, Írország· EU contribution 1 500 000 EUR· until 2032. jan.

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-RIA

  EV-enriched secretome from cord blood as a new disease modifying treatment for osteoarthritis (ExoCordOA)

  Exogenus Therapeutics Sa· Cantanhede, Portugália· EU contribution 13 000 000 EUR· until 2031. aug.· 3 countries

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Smart Platforms for Osteochondral Regeneration through on-demand Activation (SPORA)

  Instituto Superior Tecnico· Lisboa, Portugália· EU contribution 191 343 EUR· until 2028. aug.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Newly engineered lignin nanocarrier for curcumin delivery to tackle inflammation and limited synovial drug residence in osteoarthritis (LigNPsCURCDeLIV)

  University of Leeds· Leeds, Egyesült Királyság· EU contribution 276 188 EUR· until 2028. szept.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Gene-activated tri-layer 3D-bioprinted scaffold for enhanced osteochondral defect repair (GATSO-3D)

  Royal College of Surgeons in Ireland· Dublin 2, Írország· EU contribution 252 729 EUR· until 2028. júl.

  The disease is named only in the funder's project summary, not in the title.

10 of 421 running projects, newest first. Listed amounts together: 229,9 M USD + 106,0 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

Ebben a nézetben egy vizsgálat sem jelzi, hogy megosztaná a résztvevői adatokat.

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 43
• Organoids 4
• Mendelian Randomization Analysis 56
• CRISPR-Cas Systems 1
• Gene Expression Profiling 106
• Sequence Analysis, RNA 11
• Whole Genome Sequencing 3
• Exome Sequencing 1
• Proteomics 43
• Metabolomics 26
• Mass Spectrometry 5
• Flow Cytometry 7
• Immunohistochemistry 19
• Positron-Emission Tomography 6
• Magnetic Resonance Imaging 276
• Machine Learning 78
• Deep Learning 45
• Cohort Studies 148
• Genome-Wide Association Study 48

• Modeling Relationships Among Pain and Function in Individuals With Knee Osteoarthritis in the A2CPS Cohort.

  Clin J Pain, 2026. nov.

• Arthroplasty centers logistically separated from general orthopedic departments were associated with a more successful implementation of a standardized day-case setup : A Danish cohort study of 6718 procedures from a fast-track multi-center collaboration.

  Arch Orthop Trauma Surg, 2026. okt.

• Association between cemented and uncemented cups and risk of revision in patients aged 65 years or older following primary total hip arthroplasty: a study of 310,515 patients from the Nordic Arthroplasty Register Association.

  Acta Orthop, 2026. okt.

• Is intra-articular injection of high-concentration ozone (O2-O3) more effective in treating knee osteoarthritis?: A multicenter cohort study.

  Medicine (Baltimore), 2026. okt.

• Systemic sclerosis markedly impairs health-related quality of life: a single-centre tertiary cohort study with literature-based comparison to leading causes of global disease burden.

  J Glob Health, 2026. okt.

• Real-World Use of Manual Therapy and Exercise for Managing Knee Osteoarthritis-A Military Health System Analysis.

  JOSPT Open, 2026. okt.

• Prediction of 2-Year Incident Clinical Knee Osteoarthritis From Extensor Mechanism Mechanical Properties in Asymptomatic Community-Dwelling Older Adults: Prospective Cohort Study.

  JMIR Aging, 2026. szept.

• Impact of an Opioid Avoidance Protocol for ACL Reconstruction: A Pilot Sequential Cohort Study.

  J Am Acad Orthop Surg Glob Res Rev, 2026. szept.

• Association of polyethylene type with revision and dislocation risk following primary total hip arthroplasty: a population-based cohort study from the Danish Hip Arthroplasty Register.

  Acta Orthop, 2026. szept.

• Comparative Effectiveness of Intra-Articular Nanofat and Platelet-Rich Plasma Injections in Pain Relief and Functional Improvement for Unilateral Knee Osteoarthritis: A Retrospective Cohort Study.

  Pain Physician, 2026. szept.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.