Predicting Risk Factors for Exacerbation of Chronic Obstructive Pulmonary Disease
A legfontosabb adatok
- Hol
- Shanghai (Kína)A helyszín megnézése
AI-kivonat: kiket keres a vizsgálat
A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.
A vizsgálat 40 éves vagy idősebb felnőtteket keres, akiknél krónikus obstruktív tüdőbetegséget (COPD) diagnosztizáltak.
- Életkor
- 40 év vagy idősebb
- Nem
- Férfiak és nők is részt vehetnek.
- A betegség stádiuma
- Klinikailag diagnosztizált krónikus obstruktív tüdőbetegség (COPD). Stádiumot vagy súlyosságot nem ír elő.
A részvétel fő kizáró okai
- Nem tudja elvégezni a spirometriát (légzésfunkciós vizsgálat)
- Asztma
- Tüdőembólia (vérrög a tüdőben)
- Tüdőrák
- Tuberkulózis utáni maradványállapot
Gépi kiolvasás: 2026. november 12.
Helyszínek itt: Kína
- Department of Respiratory Medicine, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai, KínaContact: Yue ZhangRésztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
- Azonosító
- NCT03450603
- A regiszteradat frissítve
- 2026. március 11.
- Eredeti leírás
Exacerbations of chronic obstructive pulmonary disease (COPD) are unfavourable events in the course of disease for most COPD patients. Published evidence indicates a significant impact of exacerbations, especially if frequent, on patients' health-related quality of life (HRQL), disease progression, mortality, health care utilisation and costs. However, the severity,evolution and outcome of an exacerbation may differ significantly between patients - some patients will recover completely in a short period of time while others may die. The identification of risk factors for an adverse outcome could help in distinguishing patients who require more intense management in order to prevent failures, achieve satisfactory recovery and reduce the negative clinical and socioeconomic impact of exacerbations.The pathogenesis of COPD is still unclear, so there is no specific treatment at present .COPD was considered to be the result of a combination of environmental and genetic factors. Genetic factors play an important role in the acute exacerbation of COPD.Therefore, it is an urgent need to explore the heterogeneity of COPD phenotype from the perspective of genes and to seek individualized prevention and treatment programs.This study is intended to provide a theoretical basis for the prevention, evaluation and development of individualized treatment plans for acute exacerbation of COPD, thereby improving the prognosis of the disease.A teljes eredeti leírásKevesebb
It is Crucial to Identify Predicting Risk Factors for Exacerbation of Chronic Obstructive Pulmonary Disease in Order to Provide Adequate Intensive Therapy and Closer Follow-up
Exacerbations of chronic obstructive pulmonary disease (COPD) are unfavourable events in the course of disease for most COPD patients. Published evidence indicates a significant impact of exacerbations, especially if frequent, on patients' health-related quality of life (HRQL), disease progression, mortality, health care utilisation and costs. However, the severity,evolution and outcome of an exacerbation may differ significantly between patients - some patients will recover completely in a short period of time while others may die. The identification of risk factors for an adverse outcome could help in distinguishing patients who require more intense management in order to prevent failures, achieve satisfactory recovery and reduce the negative clinical and socioeconomic impact of exacerbations.The pathogenesis of COPD is still unclear, so there is no specific treatment at present .COPD was considered to be the result of a combination of environmental and genetic factors. Genetic factors play an important role in the acute exacerbation of COPD.Therefore, it is an urgent need to explore the heterogeneity of COPD phenotype from the perspective of genes and to seek individualized prevention and treatment programs.This study is intended to provide a theoretical basis for the prevention, evaluation and development of individualized treatment plans for acute exacerbation of COPD, thereby improving the prognosis of the disease.
Bevonási feltételek: Clinical diagnosis of Chronic obstructive pulmonary disease; aged >= 40 years.
Kizáró feltételek: lung cancer; sequelae of tuberculosis; interstitial lung disease; left cardiac insufficiency; spirometry can not be completed because of various reasons; asthma; pulmonary embolism; extensive bronchiectasis.