OCT in Diagnosis of Irregular Corneas

MI-összefoglaló

A vizsgálat saját részvételi feltételeiből. Gép olvasta ki az oldalon álló regiszterszövegből, ezért tévedhet. Hogy ki vehet részt, azt a lenti regiszterszöveg és a vizsgálat csapata dönti el.

The trial is looking for people with an irregular cornea, such as keratoconus, warpage from contact lenses, dry eye, scars or corneal dystrophies. People with healthy eyes can also join as controls.

Életkor

14 Years to 85 Years

Nem

All sexes

A betegség stádiuma

Irregular corneal shape seen on corneal mapping (topography). This can come from keratoconus, pellucid marginal degeneration, contact lens warpage, dry eye with an OSDI score ≥ 30, EBMD, scars, Salzmann's degeneration, stromal dystrophies, problems after LASIK or PRK, RK or a corneal transplant. People with keratoconus need CDVA ≥ 20/25 in the better eye. Some people may join a group followed over time or a group treated with PTK.

Korábbi kezelés

People in the keratoconus group cannot have had corneal surgery before. Healthy controls must have had no earlier eye procedures or surgeries.

A részvétel fő kizáró okai

• Unable to give informed consent or come to the study visits
• Unable to keep the eye still for OCT imaging
• Cataract, retinal disease, glaucoma or other eye conditions that may limit vision after surgery
• Pregnancy or breastfeeding
• Earlier corneal surgery for people in the keratoconus group

A regiszter feltételei, szó szerint

Nézd meg, megfelelhetsz-e

Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.

• 14 és 85 év között vagy?IgenNem

Mit akar kideríteni a vizsgálat

This main goal of this study is to improve the detection, classification, monitoring, and treatment of irregular corneas due to keratoconus, warpage, dry eye, scar, stromal dystrophies, and other corneal conditions.

A vizsgálat 3 csoportja

• Group A: Classification of Corneal Irregularities

  This group will consist of participants \>14 years old with various types of corneal irregularities. Their data will be compared against participants with healthy corneas. Data for this group will be gathered only once.

  Kezelés: Optical Coherence Tomography

• Group B: Detection of Keratoconus Progression

  Participants from Group A who are diagnosed with keratoconus will be selected for this longitudinal study to monitor keratoconus progression. They will be followed up to 4 years.

  Kezelés: Optical Coherence Tomography

• Group C: OCT-and-Topography Guided PTK

  Participants from Group A will be selected for this group if they have vision primarily limited by scars, dystrophy, or high astigmatism that could be treated by PTK. They will be followed up to 1 year.

  Kezelés: Optical Coherence Tomography