Neural Correlates of Sensory Phenomena in Tourette Syndrome
A legfontosabb adatok
- Hol
- Nashville (Egyesült Államok)A helyszín megnézése
Helyszínek itt: Egyesült Államok
- Vanderbilt University Medical CenterNashville, Egyesült ÁllamokNo longer taking part
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Vanderbilt University Medical Center
- Azonosító
- NCT03914664
- A regiszteradat frissítve
- 2026. január 14.
- Eredeti leírás
The most pervasive sensory manifestation of TS is sensory over-responsivity (SOR). SOR is defined as excessive behavioral response to commonplace environmental stimuli. SOR is an integral but poorly understood facet of the TS phenotype, one intertwined with core elements of the disorder and worse QOL. This proposal seeks to clarify the mechanistic bases of SOR in TS. Adults with with TS will be recruited 1) to complete a standardized clinical symptom assessment battery and 2) to undergo electroencephalogram (EEG), autonomic, and audio-visual monitoring during tactile and auditory stimuli paradigms, as well as at rest.A teljes eredeti leírásKevesebb
The most pervasive sensory manifestation of TS is sensory over-responsivity (SOR). SOR is defined as excessive behavioral response to commonplace environmental stimuli. SOR is an integral but poorly understood facet of the TS phenotype, one intertwined with core elements of the disorder and worse QOL. This proposal seeks to clarify the mechanistic bases of SOR in TS. Adults with with TS will be recruited 1) to complete a standardized clinical symptom assessment battery and 2) to undergo electroencephalogram (EEG), autonomic, and audio-visual monitoring during tactile and auditory stimuli paradigms, as well as at rest.
Bevonási feltételek: Diagnosis of Tourette syndrome or other chronic tic disorder; ≥ 18 years of age; Ability to complete survey instruments; English fluency (given that all scales are validated in English); ≥ 18 years of age AND age within 5 years of a participant in the TS arm of same biological sex (for purposes of age- and sex-matching); Ability to complete survey instruments; English fluency (given that all scales are validated in English).
Kizáró feltételek: Use of any psychotropic medications within the past 30 days; Known diagnosis of autism spectrum disorder, developmental delay, cerebral palsy, other significant neurologic disease, schizophrenia, or psychotic disorders will be excluded, in order to lessen potentially confounding factors; (Note: Patients with OCD, ADHD, anxiety, and/or depression will be permitted, given that these diagnoses are widely prevalent in the adult TS population.); Use of anti-seizure medications, stimulants, or other psychotropic medications known to alter EEG signal; Any neurologic or psychiatric diagnoses; History of tics; Recreational substance use within past 30 days; Recreational substance use within past 30 days.