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Effect of Therapeutic Joint Arthrocentesis on Pain and Quadriceps Function in Patients With Knee Osteoarthritis

A legfontosabb adatok

Ki végzi
Colorado Joint Replacement
Hol
Aurora és Denver (Egyesült Államok)Mind a 2 helyszín megnézése
Azonosító
Állapot
Befejeződött
Résztvevők
20 fő vett részt
Kezdés
2019. dec. 5.
Befejezés
2024. ápr. 10.
A vizsgálat típusa
Beavatkozással járó, 2 csoport
A vizsgált kezelések
  • Arthrocentesis
A regiszteradat frissítve
2026. november 4.

Ki vehet részt

Életkor
18 év felett
Nem
Nők és férfiak
Egészséges önkéntesek
Részt vehetnek

A regiszter feltételei, szó szerint

Mind a 14 feltétel megnézéseKevesebb

Ki vehet részt

  • Patients aged 18 years or older with mild (1+) to severe (3+) knee effusion associated with underlying osteoarthritis (Kellgren and Lawrence grade II or higher) that undergo therapeutic aspiration
  • Patients with symptomatic primary total knee arthroplasty without infection (as verified by prior aspiration) with moderate to severe effusion electing for therapeutic arthrocentesis. Must be minimum of 3 months from index surgery to be included

Ki nem vehet részt

  • Patients with revision knee arthroplasty, unicompartmental arthroplasty or other repair/reconstruction surgery
  • Patients with effusion related to trauma or another underlying condition (ie. fracture, ligamentous injury, hemarthrosis)
  • Patients with knee effusion associated with septic arthritis or periprosthetic knee infection as determined from knee arthrocentesis
  • Patients with underlying muscular disorder (ie. Stroke, cerebral palsy, multiple sclerosis, polymyalgia, fibromyalgia, muscular dystrophy, etc.)
  • Patients with active cancer in the area
  • Blood clotting disorders, sickle cell disease or trait, or chronic anticoagulation
  • Patients with known history of gout or with synovial fluid samples testing positive for urate of calcium pyrophosphate crystals
  • Invasive or injectable therapy within the last 6 months in the involved knee, to include, but not limited to, arthrocentesis, corticosteroid, hyaluronic acid, platelet-rich plasma, prolotherapy, stem cell therapy, or genicular nerve block
  • Patients with inflammatory arthritis (ie. JIA, RA, psoriatic arthritis, etc)
  • Patients with symptomatic hip pain
  • Patients with pacemakers
  • Patients who are pregnant

Helyszínek itt: Egyesült Államok

  • University of Colorado DenverAurora, Egyesült Államok
  • Colorado Joint ReplacementDenver, Egyesült Államok

A vizsgálatról

Mit akar kideríteni a vizsgálat

This will be prospective study of patients with knee effusion associated with degenerative osteoarthritis or symptomatic primary total knee arthroplasty that undergo therapeutic joint arthrocentesis. The diagnosis of knee osteoarthritis will be based on knee radiographs (including AP, Rosenburg view, lateral and Merchant views) read and interpreted by one of our clinical providers (PA, Fellow or Surgeon). Patients with at least Grade II Kellgren and Lawrence changes or higher will be included in the osteoarthritis group. Patients in the arthroplasty group must have had a primary total knee arthroplasty without infection (as determined by knee aspirate) to be included. Patients will be clinically evaluated at the time of their visit for presence of a knee effusion using a stroke test and graded on a 5-point scale (zero, trace, 1+, 2+, or 3+) which has shown good interrater reliability. Patients with a mild to severe effusion (1+ to 3+) will considered for the study. Patients having significant pain associated with their effusion will be offered a therapeutic arthrocentesis as part of their treatment plan discussion. This is a pre-post test design in which outcome measures will be collected immediately pre-arthrocentesis and immediately post arthrocentesis. Additionally, there will be an optional 7-10 follow up visit where outcomes measures will be collected again, should the participant choose to return to this visit.

A vizsgálat 2 csoportja

  • Primary OsteoarthritisA vizsgált kezelés

    Patients with native knees and effusions will participate in this arm.

    Kezelés: Arthrocentesis

  • Primary TKAA vizsgált kezelés

    Patients with total knee replacements will participate in this arm.

    Kezelés: Arthrocentesis

Adatok és források

Regiszteradat
Szerepel a ClinicalTrials.gov-on.
A regiszteradat frissítve
2026. november 4.