Transpyloric Stenting as a Predictor for G-POEM for Refractory Gastroparesis
Megadott ok: Excessive stent migration.
A legfontosabb adatok
- Hol
- Chicago (Egyesült Államok)A helyszín megnézése
Helyszínek itt: Egyesült Államok
- Northwestern UniversityChicago, Egyesült ÁllamokNo longer taking part
A vizsgálat adatai
- Ki végzi
- Northwestern University
- Azonosító
- NCT04287647
- A regiszteradat frissítve
- 2026. június 1.
- Eredeti leírás
This is a prospective sham study to investigate the role of transpyloric stenting with lumen apposing metal stent (LAMS) as a predictor for clinical response to gastric per-oral endoscopic pyloromyotomy (GPOEM) for refractory gastroparesis. The study hypothesizes that clinical improvement with transpyloric stenting in patients with refractory gastroparesis is a predictor of subsequent clinical success of GPOEM.A teljes eredeti leírásKevesebb
Transpyloric Stenting for Refractory Gastroparesis Prior to Gastric Per-Oral Endoscopic Myotomy: A Prospective Sham Study
This is a prospective sham study to investigate the role of transpyloric stenting with lumen apposing metal stent (LAMS) as a predictor for clinical response to gastric per-oral endoscopic pyloromyotomy (GPOEM) for refractory gastroparesis. The study hypothesizes that clinical improvement with transpyloric stenting in patients with refractory gastroparesis is a predictor of subsequent clinical success of GPOEM.
Bevonási feltételek: Adult patients greater than 18 years of age with gastroparesis refractory to standard medical therapy (lifestyle and diet modifications, prokinetics) or contraindication to standard therapies (e.g. allergies to prokinetic agents); Patients with diabetic, idiopathic or post-surgical gastroparesis; Patients with confirmed diagnosis of gastroparesis via gastric emptying study (abnormal gastric emptying will be defined as ≥10 % residual activity at 4 h on a standardized nuclear medicine TC-99 m sulfur colloid solid-phase gastric emptying study).
Kizáró feltételek: Patients with prior history of gastroenteric anastomosis or any GI surgeries with pyloric involvement; Patients with gastroesophageal malignancy; Patients with uncorrectable coagulopathy defined by INR >1.5 or platelets <50; Patients who are unable to tolerate upper endoscopy secondary to cardiopulmonary instability or other contraindications to endoscopy; Patients with cirrhosis; Patients who are pregnant or breastfeeding.