Home Blood Pressure Monitoring in Kidney Transplant Recipients

Ki vehet részt

• Kidney transplant recipient
• Male or female subject ≥ 18 years old
• Any or more of the following at the baseline clinic; Conventional office BP ≥130 mmHg systolic and/or ≥ 80 mmHg diastolic; HBPM ≥125 mmHg systolic and/or ≥ 80 mmHg diastolic measured within the last 3 months (see appendix 1 for details on methodology); Daytime ambulatory blood pressure monitoring (ABPM) ≥125 mmHg systolic and/or ≥ 80 mmHg diastolic measured within the last 3 months
• Signed informed consent and expected cooperation of the patient for the treatment and follow up
• Have a national personal identification number and not be expected to emigrate during study
• Enlisted in the Norwegian Renal Registry

Ki nem vehet részt

• Current use of ≥ 4 antihypertensive medications
• Female participant who is pregnant, lactating or planning pregnancy during the trial (management of essential hypertension in pregnancy is different)
• Any reason likely limiting adherence to interventions, as judged by the investigator; examples include active alcohol or substance abuse within the last 12 months, significant poor compliance with medications or attendance at clinic visits, residence in a nursing home, dementia, other medical or psychiatric conditions that may interfere with study participation
• Severe white-coat hypertension, e.g. patients already treated solely based on home BP values
• Multi-organ transplants (e.g. heart, lung, liver), though pancreas or beta-cell islet transplant is allowed
• Standing systolic BP < 110 mmHg (to avoid adverse events). Measured after one and three minutes of standing. Not applicable if unable to stand due to wheelchair use
• Diagnosed atrial fibrillation (automated monitors not validated)
• Unwilling to self-monitor
• Arm circumference too large or small to allow accurate BP measurement with available device (22-42 cm)
• Graft- or life expectancy less than 2 years, as judged by the investigator
• More than half of regular appointments planned as remote (e.g. phone or video) consultations