Irreversible Electroporation of Unresectable Liver Tumors

Ki vehet részt

• Primary or secondary cancer of the liver
• Largest tumor diameter ≤5 cm in any plane
• Tumor must be deemed as unresectable and unsuitable for other established curative liver directed therapies
• Treatment must be given with curative intent
• Patients must be able to give informed consent

Ki nem vehet részt

• Metal stents or other metallic objects near the ablation zone (unless the stent can be replaced with a plastic stent prior to IRE)
• Radiological signs of synchronous intra- or extrahepatic disease, unless curative intended therapy is planned
• Implanted electronic devices e.g. cardiac pacemakers or other electrostimulators
• Severe allergies to anesthetic agent, paralytic agent or any of the equipment used during treatment
• International Normalized Ratio (INR)>1.5
• Tumor is inaccessible e.g. due to venous dilation etc. (assessed with preoperative ultrasound)
• American Society of Anesthesiologists (ASA) score >3
• Eastern Cooperative Oncology Group (ECOG) performance status >2
• Child-Pugh class C
• Pregnancy
• Persistent atrial fibrillation
• Patient is referred from a hospital outside of Denmark