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Psychotherapy for PTSD Among Veterans Also Receiving Drug or Alcohol Treatment

A legfontosabb adatok

Ki végzi
Center for Veterans Research and Education
Hol
Atlanta, Cincinnati, Cleveland, Durham, Hines, Madison, Minneapolis, New Orleans, Philadelphia, Salt Lake City, San Diego, Seattle, Syracuse és Tampa (Egyesült Államok)Mind a 14 helyszín megnézése
Azonosító
Állapot
Befejeződött
Résztvevők
426 fő vett részt
Kezdés
2020. dec. 8.
Befejezés
2024. ápr. 26.
A vizsgálat típusa
Beavatkozással járó, 2 csoport
A vizsgált kezelések
  • Prolonged Exposure Therapy
  • Cognitive Processing Therapy
  • Present Centered Therapy
A regiszteradat frissítve
2024. június 25.

Ki vehet részt

Életkor
18 év felett
Nem
Nők és férfiak
Egészséges önkéntesek
Nem vehetnek részt

A regiszter feltételei, szó szerint

Mind a 10 feltétel megnézéseKevesebb

Ki vehet részt

  • Initiate an episode of outpatient SUD treatment at an enrolled facility
  • meet DSM-5 criteria for a current SUD (Tobacco Use Disorder alone is not sufficient for inclusion)
  • Report substance use in the past 30 days (or in the 30 days prior to entering a controlled environment if exiting said controlled environment at time of enrollment)
  • meet DSM-5 criteria for PTSD
  • provide informed consent and be willing to be randomized to PTSD treatment condition
  • agree to not receive non-study, active psychotherapy for PTSD during study treatment

Ki nem vehet részt

  • Severe cognitive impairment
  • Current suicidal or homicidal intent with a specific plan
  • Unstable psychotic or manic symptoms not attributable to SUD
  • More than 30 days between index outpatient SUD intake/treatment planning appointment \& consent or more than 90 days between the index outpatient SUD visit and the first PTSD psychotherapy session

Helyszínek itt: Egyesült Államok

  • Atlanta VA Medical CenterAtlanta, Egyesült Államok
  • Cincinnati VA Healthcare SystemCincinnati, Egyesült Államok
  • Louis Stokes Cleveland VA Medical CenterCleveland, Egyesült Államok
  • Durham VA Medical CenterDurham, Egyesült Államok
  • Edward Hines Jr VA HospitalHines, Egyesült Államok
  • Madison VA Medical CenterMadison, Egyesült Államok
  • Minneapolis VA Medical CenterMinneapolis, Egyesült Államok
  • Southeast Louisiana Veterans Health Care SystemNew Orleans, Egyesült Államok
  • Philadelphia VA Medical CenterPhiladelphia, Egyesült Államok
  • Salt Lake City VA Healthcare SystemSalt Lake City, Egyesült Államok
  • San Diego VA Healthcare SystemSan Diego, Egyesült Államok
  • Puget Sound VA Healthcare SystemSeattle, Egyesült Államok
  • Syracuse VA Medical CenterSyracuse, Egyesült Államok
  • Tampa VA Medical CenterTampa, Egyesült Államok

A vizsgálatról

Mit akar kideríteni a vizsgálat

Many people who have posttraumatic stress disorder (PTSD) also struggle with problematic alcohol or drug use (substance use disorders [SUD]). Patients with both conditions prefer PTSD be treated alongside SUD. However, clinicians don't know if treatments that have been found to help those with PTSD work as well for people who also have SUD. This often leads to delaying PTSD treatment or using psychotherapies without research support. Trauma-focused psychotherapy (TFT) is the type of psychotherapy for PTSD that has been studied most often among people with both PTSD and SUD. It reduces symptoms of PTSD and substance use, although it might not work as well in those who have SUD as those who do not. Further, many patients with both PTSD and SUD do not complete TFT. Another strategy for treating PTSD is non-trauma-focused psychotherapy (NTFT). One NTFT, Present Centered Therapy, has been found to reduce symptoms of PTSD and more patients are able to complete NTFT than are able to finish TFT. However, no one has studied how well Present Centered Therapy works among patients who also have SUD.

A teljes eredeti leírásKevesebb

We will test which approach (TFT of NTFT) is better for reducing symptoms of PTSD and which is more likely to be completed by patients with both PTSD and SUD at VA healthcare facilities. We will also test to see whether some participants did better than others, so we can learn how to individualize treatment recommendations to patients. Participants will be assigned by chance to either TFT of NTFT. Patients assigned to TFT will receive either Prolonged Exposure or Cognitive Processing Therapy; both are weekly psychotherapies focused on addressing thoughts and/or memories related to their trauma. Those assigned to NTFT will receive Present Centered Therapy, a weekly psychotherapy in which patients learn about how PTSD relates to their current difficulties and problem solve current life difficulties. All participants will also receive SUD treatment. Participants will answer questions about their symptoms and experience with treatment before, right after they finish, and three and six months after they finish PTSD treatment. At the end of the study we will compare which treatment approach worked better to decrease PTSD symptom severity and which treatment patients were better able to complete. We will also track other outcomes that are important to patients (e.g., how they are doing in their relationships).

A vizsgálat 2 csoportja

  • Trauma-Focused TherapyA vizsgált kezelés

    Patients randomized to Trauma Focused Therapy will receive either Prolonged Exposure (PE) or Cognitive Processing Therapy (CPT). According to standard VA practice, assignment will be determined according to which trauma-focused therapy the assigned provider is verified to provide; if the assigned therapist is verified in both PE and CPT, the provider will decide which treatment to deliver. PE and CPT are both recommended as frontline treatments by all published PTSD guidelines. The standard treatment length will be 12 weekly sessions; however, patients and providers can collaboratively agree to early completion or extension as warranted.

    Kezelés: Prolonged Exposure Therapy és Cognitive Processing Therapy

  • Non-Trauma-Focused TherapyA vizsgált kezelés

    Those randomized to non-trauma-focused therapy will receive present centered therapy (PCT). Originally designed as a strong comparator for psychotherapy research that included the components of "good therapy," PCT is now a bona-fide PTSD treatment suggested at the second tier in multiple clinical practice guidelines. The standard treatment length will be 12 weekly sessions; however, patients and providers can collaboratively agree to early completion or extension as warranted.

    Kezelés: Present Centered Therapy

Adatok és források

Regiszteradat
Szerepel a ClinicalTrials.gov-on.
Hivatalos cím
Comparative Effectiveness of Trauma-Focused and Non-Trauma-Focused Treatment Strategies for PTSD Among Those With Co-Occurring SUD (COMPASS)
Publikációk
A regiszteradat frissítve
2024. június 25.