The Safety of Intravenous Tranexamic Acid in Patients Undergoing Supratentorial Meningiomas Resection
Ennek a vizsgálatnak nincs helyszíne itt: Egyesült Államok.
Egy országban van helyszíne. Válassz országot, hogy lásd a helyszíneket.
A vizsgálat adatai
- Ki végzi
- Beijing Tiantan Hospital
- Azonosító
- NCT04595786
- A regiszteradat frissítve
- 2025. március 4.
- Eredeti leírás
Growing evidence of Tranexamic Acid (TXA) being used to reduce blood loss and blood transfusions in various guidelines. However, the adverse effects of TXA especially seizure has always been a problem of concern, especially in neurosurgery. Therefore, this study aims to provide a scientific evidence for the safety of TXA in supratentorial meningiomas resection patients.A teljes eredeti leírásKevesebb
A Randomized, Parallel-group, Placebo Control, Non-inferiority Trial to Investigate the Safety of Intravenous Tranexamic Acid in Patients Undergoing Supratentorial Meningiomas Resection
Growing evidence of Tranexamic Acid (TXA) being used to reduce blood loss and blood transfusions in various guidelines. However, the adverse effects of TXA especially seizure has always been a problem of concern, especially in neurosurgery. Therefore, this study aims to provide a scientific evidence for the safety of TXA in supratentorial meningiomas resection patients.
Bevonási feltételek: 1) age 18-80 years; 2) American Society of Anesthesiologist (ASA) classification score I~III.
Kizáró feltételek: 1) allergic to tranexamic acid; 2) preoperative seizures; 3) history of thrombotic disease; 4) chronic kidney disease; 5) breastfeeding or pregnancy; 6) refuse to participate in the study.