Feasibility Study on Radiofrequency-Based Selective Electrothermolysis to Investigate Its Effects on Human Skin
Megadott ok: Funding were insufficient to complete
A legfontosabb adatok
- Hol
- Baltimore (Egyesült Államok)A helyszín megnézése
Helyszínek itt: Egyesült Államok
- Johns Hopkins School of MedicineBaltimore, Egyesült ÁllamokNo longer taking part
A vizsgálat adatai
- Ki végzi
- Johns Hopkins University
- Azonosító
- NCT05066113
- A regiszteradat frissítve
- 2026. június 9.
- Eredeti leírás
This research is being done to assess the effect of radiofrequency (RF)-based treatment on skin and skin conditions.A teljes eredeti leírásKevesebb
This research is being done to assess the effect of radiofrequency (RF)-based treatment on skin and skin conditions.
Bevonási feltételek: For primary objective: healthy volunteers and HS patients between 22 and 70 years of age; Participants must be healthy enough to undergo multiple skin biopsy in the opinion of the investigator; Participants must provide informed consent; Participants must have the ability and willingness to follow all study procedures, attend scheduled visits, and successfully complete the study; Participants must have the ability to understand and communicate with the investigator; For HS patients, participants will have localized disease to the axillae, mild to moderate severity and no evidence of active infection as assessed by the investigator.
Kizáró feltételek: Participants on systemic steroids; Participants with significant medical history or concurrent illness that the investigator feels is not safe for biopsy or study participation; Pregnant or nursing participants (qualitative human chorionic gonadotropin (hCG) testing will be performed prior to each treatment); Participants who have taken oral/topical antihistamines, oral/topical analgesics, and/or other medications that the investigators believe will impact the study; Participants who are currently taking or who have taken in the past 12 months any medications that may impair wound healing, such as systemic retinoids; Recently treated for current skin diseases that would affect clinical evaluation; Participants with bleeding disorders; Participants with any active infections or currently treated infections; Participants with allergy to anesthetics; Participants with a history of keloids or hypertrophic scars within the past 10 years; Participants unable to provide informed consent; Known contraindications to selective electrothermolysis treatment; Immunocompromised patients; Participants on immune modulators; Participants on blood thinners; Noncompliant participants; Participants who cannot undergo motor strength and sensory testing required to assess for adverse events in this study.