The TRAMPOLINE VT Study

A regiszter feltételei, szó szerint

Mit akar kideríteni a vizsgálat

This non-randomised, prospective trial will examine the feasibility and efficacy of VT ablation guided by activation mapping using the Octaray and Optrell catheters. Annotation algorithms within the CARTO3 electro-anatomical mapping system will be integrated with 3D scar segmentation data from cardiac MRI (ADAS-VT), and extrastimulus voltage mapping will identify sites of interest for focussed activation mapping. The investigators hypothesise that the examination of these data will identify critical target sites for ablation. Intra-procedural diagnostic performance of the Octaray and Optrell catheters will be assessed as the primary outcome, and will be compared with the standard of care. Secondary, clinical outcomes - primarily the need for ICD therapies at 12 months post ablation - will be compared with propensity-matched controls undergoing substrate-based ablation alone. Follow-up MRI scans will review the impact of ablation on the elimination of conduction channels.

A vizsgálat 2 csoportja

• Octaray catheterA vizsgált kezelés

  VT ablation guided by activation mapping using the Octaray catheter and integrated cardiac MRI data.

• Standard of careMár használt kezelés, összehasonlításként

  Identified retrospectively from registry data: propensity matched-controls undergoing VT ablation guided by substrate-modification alone.