Serotonin Role on Brain Circuits Involved in Food Avoidance in Anorexia Nervosa

Ki vehet részt

• Anorexia nervosa common features : fear of weight gain, dysmorphophobia, BMI < 17.5 kg/ m², amenorrhea
• Absence of food compulsions and purges
• Subgroup 1 (15 subjects) : STAI Y2 anxiety score > 61
• Subgroup 2 (15 subjects) : STAI Y2 anxiety score < 51
• BMI between 18.5 and 25 kg/ m²
• Absence of a psychological profile of eating disorder or other psychiatric disorders

Ki nem vehet részt

• Subject treated during the last three months with neuroleptics, and antiparkinsonian drugs, monoamine oxidase (MAO)-A or monoamine oxidase (MOA)-B inhibitors, tricyclic antidepressants, 5HT reuptake inhibitors, thymo regulators (lithium), antiepileptic dugs, codeine derivatives, morphinics, tramadol-containing products (Topalgic, …),dopaminergic drugs
• Subjects with suspected pregnancy; Test β human chorionic gonadotropin (HCG) positive prior to examination
• Subject with heart failure
• Subjects with an oral contraception and breastfeeding woman
• Subjects for whom MRI is contraindicated (pacemaker, intracerebral clips, prosthesis made of ferromagnetic material or claustrophobia)
• Subjects unable to sign written consent for participation in the study
• Subject deprived of liberty by a judicial or administrative decision

Egyéb feltételek

• Common Criteria for inclusion :
• Signature of written consent
• Subject affiliated or entitled to a social security scheme