MINDS Imaging Ancillary Study
A legfontosabb adatok
- Hol
- Ann Arbor, Atlanta, Boston, Charleston, Cincinnati, Houston, Indianapolis, Milwaukee, New York, Philadelphia, Pittsburgh és Salt Lake City (Egyesült Államok)Mind a 12 helyszín megnézése
Helyszínek itt: Egyesült Államok
- University of MichiganAnn Arbor, Egyesült ÁllamokNo longer taking part
- Emory UniversityAtlanta, Egyesült ÁllamokNo longer taking part
- Boston Children's HospitalBoston, Egyesült ÁllamokNo longer taking part
- Medical University of South CarolinaCharleston, Egyesült ÁllamokNo longer taking part
- Cincinnati Children's Hospital Medical CenterCincinnati, Egyesült ÁllamokNo longer taking part
- Baylor College of MedicineHouston, Egyesült ÁllamokNo longer taking part
- Indiana UniversityIndianapolis, Egyesült ÁllamokNo longer taking part
- Medical College of WisconsinMilwaukee, Egyesült ÁllamokNo longer taking part
- Icahn School of Medicine at Mount SinaiNew York, Egyesült ÁllamokNo longer taking part
- Children's Hospital of PhiladelphiaPhiladelphia, Egyesült ÁllamokNo longer taking part
- Children's Hospital of Pittsburgh of UPMCPittsburgh, Egyesült ÁllamokNo longer taking part
- University of UtahSalt Lake City, Egyesült ÁllamokNo longer taking part
A vizsgálat adatai
- Ki végzi
- University of Pittsburgh
- Azonosító
- NCT05270356
- A regiszteradat frissítve
- 2025. október 31.
- Eredeti leírás
This study is an ancillary study to the NHLBI-funded Pediatric Heart Network (PHN) "Multi-Institutional Neurocognitive Discovery Study" (MINDS) in Adult Congenital Heart Disease (ACHD). The MINDS-ACHD" study will recruit 500 complex CHD patients between18-30 years old. The investigators propose to quantitate multi-modal neuroimaging biomarkers (brain injury, structure and physiology) which are not only important components of brain and cognitive reserve but can be predictive of neurocognitive decline and early onset of dementia in the aging non-CHD population.A teljes eredeti leírásKevesebb
This study is an ancillary study to the NHLBI-funded Pediatric Heart Network (PHN) "Multi-Institutional Neurocognitive Discovery Study" (MINDS) in Adult Congenital Heart Disease (ACHD). The MINDS-ACHD" study will recruit 500 complex CHD patients between18-30 years old. The investigators propose to quantitate multi-modal neuroimaging biomarkers (brain injury, structure and physiology) which are not only important components of brain and cognitive reserve but can be predictive of neurocognitive decline and early onset of dementia in the aging non-CHD population.
Bevonási feltételek: Participation in and completion of MINDS parent study procedures. The inclusion criteria for the MINDS parent study consists of ACHD patients aged 18 - 30 years with moderate and severely complex CHD.
Kizáró feltételek: Implantable device (i.e., pacemaker; defibrillator; ferromagnetic aneurysm clips; cochlear implant; gastric reflux device; internal insulin pump; pacing leads; neurostimulation system) that cannot be cleared for scanning at 3T; Braces or orthodontic appliances that cannot be removed prior to scanning and/or cannot be cleared for scanning at 3T; Individuals with mild complexity lesions; Individuals with MRI contraindications will be excluded from study participation. Contraindications include, but are not limited, to:; Pregnancy or breast feeding; Claustrophobia or inability to lie still for an extended period; Foreign body (i.e., metallic splinter in the eye; bullet or grenade fragments); Individuals who are unable to participate in the informed consent process or complete the study questionnaire will also be excluded from participation.