The Effect of Acute Exercise on Cardiac Autonomic, Cerebrovascular, and Cognitive Function in Spinal Cord Injury
A legfontosabb adatok
- Ki végzi
- State University of New York at Buffalo
- Hol
- Buffalo (Egyesült Államok)A helyszín megnézése
- Azonosító
- Állapot
- Leállítva
- Résztvevők
- 6 fő vett részt
- Kezdés
- 2022. szept. 6.
- Befejezés
- 2024. dec. 18.
- A vizsgálat típusa
- Beavatkozással járó, 2 csoportAz egyik csoport egy már használt kezelést kap, összehasonlításként.
- A vizsgált kezelések
- One bout of moderate-intensity sub-maximal aerobic exercise
- A regiszteradat frissítve
- 2025. március 6.
- Miért állt le
- We have enrolled all the required participants for this pilot study.
Ki vehet részt
- Életkor
- 18 év – 55 év
- Nem
- Nők és férfiak
- Egészséges önkéntesek
- Részt vehetnek
A regiszter feltételei, szó szerint
Mind a 14 feltétel megnézéseKevesebb
Ki vehet részt
- Spinal cord injury group:
- Males or females with chronic SCI (i.e. at least 6 months after the initial injury)
- International Standard for Neurological Classification of SCI (ISNCSCI) A-D
- Neurological level of injury C6 or below
- 18-55 years old
- Proficient in English
- Able to detect middle cerebral artery blood velocity (MCAv) and/or posterior cerebral artery blood velocity (PCAv) signals through TCD; Non-injured controls:
- Males or females without SCI
- 18-55 years old
- Proficient in English
- Able to detect MCAv and/or PCAv signals through TCD
Ki nem vehet részt
- Cardiovascular, pulmonary or respiratory diseases, or diabetes mellitus, any other diseases/disorders affecting cardiac autonomic nervous system, such as glaucoma and attention deficit hyperactivity disorder (ADHD)
- Color Blindness
- Pregnancy
Helyszínek itt: Egyesült Államok
- Department of Rehabilitation Sciences at University at BuffaloBuffalo, Egyesült ÁllamokNo longer taking part
A vizsgálatról
Mit akar kideríteni a vizsgálat
The aims of this proposal are to: 1) investigate whether individuals with spinal cord injury (SCI) demonstrate cardiac autonomic, cerebrovascular, and cognitive dysfunctions compared to non-injured age- and sex-matched controls in the following conditions: supine rest and head-up tilt/face-cooling test; 2) examine if autonomic completeness/ incompleteness, physical activity, and psychological distress are predictors for dysfunctions during supine rest and head-up tilt/face cooling conditions in SCI individuals; 3) examine if one bout of moderate-intensity aerobic exercise temporarily improves cardiac autonomic and cerebrovascular functions and thereby improves cognition when in supine rest and head- up tilt/face cooling conditions. The study will include an initial visit and an experimental visit to our lab. Three groups of participants will be included in this study: Group 1, SCI with acute exercise; group 2, SCI with rest-control; and group 3, age- and sex-matched non-injured individuals. Cardiovascular variables, such as heart rate variability, blood pressure variability, and cerebrovascular variables, such as cerebral blood flow velocity and oxygenated hemoglobin, and cognitive performance will be examined. The investigator hypothesizes that individuals with SCI will have impaired cardiac autonomic, cerebrovascular, and cognitive functions compared to the non-injured controls, and an acute exercise can improve those functions. Autonomic completeness/incompleteness, physical activity, and psychological distress are significant factors that predict cardiac autonomic, cerebrovascular, and cognitive functions in individuals with SCI.
A vizsgálat 2 csoportja
- CONMár használt kezelés, összehasonlításként
Age-and sex-matched healthy controls with exercise intervention
Kezelés: One bout of moderate-intensity sub-maximal aerobic exercise
- SCIA vizsgált kezelés
Individuals with spinal cord injury
Kezelés: One bout of moderate-intensity sub-maximal aerobic exercise
Adatok és források
- Regiszteradat
- Szerepel a ClinicalTrials.gov-on.
- Hivatalos cím
- The Effect of Acute Exercise on Cardiac Autonomic, Cerebrovascular, and Cognitive Function in Spinal Cord Injury: a Pilot Study
- A regiszteradat frissítve
- 2025. március 6.