Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?
A legfontosabb adatok
- Hol
- Richmond (Egyesült Államok)A helyszín megnézése
Neked szólhat?
Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.
- 12 és 21 év között vagy?
Forrás: NCT05618054: ki vehet részt
Helyszínek itt: Egyesült Államok
- Virginia Commonwealth UniversityRichmond, Egyesült ÁllamokContact: Gisela Chelimsky, M.D.Résztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Virginia Commonwealth University
- Azonosító
- NCT05618054
- A regiszteradat frissítve
- 2026. április 21.
- Eredeti leírás
This study is being conducted to see how people with Postural tachycardia syndrome (POTS) make sense of the things they see. The information may help doctors to learn more about how the different parts of people's brains communicate.A teljes eredeti leírásKevesebb
Pediatric POTS: Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?
This study is being conducted to see how people with Postural tachycardia syndrome (POTS) make sense of the things they see. The information may help doctors to learn more about how the different parts of people's brains communicate.
Bevonási feltételek: Females 12-21 years old; Able to communicate and provide consent/assent; English speaking; Diagnosed with POTS (POTS will be defined standardly as a symptomatic ≥ 40 bpm rise in heart rate without a drop in blood pressure and with symptoms of orthostatic intolerance clinically); Age-matched healthy control subjects: no POTS or other neurological disorders.
Kizáró feltételek: Treatment with a drug or medical device within the previous 30 days that has not received regulatory approval; Any major surgical intervention with general anesthesia in the last 60 days and minor procedure, such as tooth extraction, endoscopy, etc., with local or conscious sedation within 7 days; Inflammatory arthritis, connective tissue or auto-immune disorder; Any chronic neurological disorder besides POTS; Neuropathy, central nervous system disorder (e.g., Cerebral palsy, developmental delay, seizure disorder, MS, stroke, etc.); Any condition that in the judgment of the investigator would interfere with the patient's ability to provide informed consent, comply with study instructions, place the patient at increased risk, or which would clearly confound the interpretation of the study results (specific reason will be documented); Evidence of unstable medical disorder, such as kidney (rising creatinine, or end-stage renal failure) or liver impairment (rising AST or ALT, or end-stage with coagulopathy), poorly controlled significant cardiovascular (CHF), respiratory, endocrine (diabetes - A1c > 9 - or untreated thyroid dysfunction) or uncontrolled psychiatric illness (such as untreated depression, psychosis, etc.); Use of hormones (except insulin, thyroid replacement or oral contraceptives, which will be carefully documented); Current substance or alcohol abuse; Any on-going or pending medical, health or disability related litigation, or current pursuit of disability; Chronic use of narcotics for pain; Claustrophobia or any metal hardware that may interfere with MRI; Investigators and study staff.