Tissue Destruction and Healing in Celiac Disease
A legfontosabb adatok
- Hol
- Chicago, Pasadena és Rochester (Egyesült Államok)Mind a 3 helyszín megnézése
Neked szólhat?
Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.
- 18 és 75 év között vagy?
Forrás: NCT05680012: ki vehet részt
Helyszínek itt: Egyesült Államok
- The University Of ChicagoChicago, Egyesült ÁllamokContact: Bana Jabri, MDRésztvevőt keres
- California Institute of TechnologyPasadena, Egyesült ÁllamokContact: Rustem Ismagilov, PhDToborzás még nem indult
- Mayo ClinicRochester, Egyesült ÁllamokContact: Joseph Murray, MDRésztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- University of Chicago
- Azonosító
- NCT05680012
- A regiszteradat frissítve
- 2026. július 28.
- Eredeti leírás
The purpose of this clinical study is to learn more about celiac disease pathogenesis and clinical symptoms. In particular, this study will examine the interactions between biological factors such as, intestinal epithelial cells, microbiota, immune system, genetics, and gluten and their effect on celiac disease clinical symptoms, and severity of tissue destruction and its ability to heal in individuals with celiac disease. Information collected in the study will help researchers to generate better resources to advance celiac disease patient care.A teljes eredeti leírásKevesebb
The purpose of this clinical study is to learn more about celiac disease pathogenesis and clinical symptoms. In particular, this study will examine the interactions between biological factors such as, intestinal epithelial cells, microbiota, immune system, genetics, and gluten and their effect on celiac disease clinical symptoms, and severity of tissue destruction and its ability to heal in individuals with celiac disease. Information collected in the study will help researchers to generate better resources to advance celiac disease patient care.
Bevonási feltételek: Gluten challenge group:; Age 18 to 75 years old; Diagnosis of Celiac disease for at least 12 months by intestinal biopsy; Follow a strict gluten-free diet for at least the 12 consecutive months; Gluten de-challenge group:; Age 18 to 75 years old; Showing typical celiac disease symptoms; Not on a gluten-free diet; Control group:; Age 18 to 75 years old; Females who are not pregnant.
Kizáró feltételek: Gastrointestinal illness within the 4-week period prior to screening; Taking antibiotics, proton pump inhibitors, aspirin, or non-steroidal anti-inflammatory drugs; Prior gastrointestinal surgery; Diagnosis of any severe complication of celiac disease; Diagnosis of other chronic, active GI disease; Any clinically significant diseases; History of significant substance or alcohol abuse; Diagnosis of blood clotting disorders; Gluten de-challenge group:; History of chronic inflammatory gastrointestinal disease; History of lymphoproliferative disease; Uncontrolled blood clotting disorders; Any clinically significant diseases; History of significant substance or alcohol abuse; Control group:; Family history of celiac disease; Gluten challenge group:; Selective IgA deficiency; Severe reaction to gluten exposure; Pregnant or lactating; Known intestinal inflammation; Taking of antiplatelet agents or anticoagulants.