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LeállítvaFázis nélkül

Stress and Neurofeedback in Anorexia Nervosa

A legfontosabb adatok

Ki végzi
University of California, San Diego
Hol
San Diego (Egyesült Államok)A helyszín megnézése
Azonosító
Állapot
Leállítva
Résztvevők
2 fő vett részt
Kezdés
2023. ápr. 26.
Befejezés
2025. márc. 25.
A vizsgálat típusa
Beavatkozással járó
A vizsgált kezelések
  • Negative Affect Task
A regiszteradat frissítve
2025. március 30.
Miért állt le
No funding received

Ki vehet részt

Életkor
18 év – 45 év
Nem
Nők és férfiak
Egészséges önkéntesek
Részt vehetnek

A regiszter feltételei, szó szerint

Mind a 45 feltétel megnézéseKevesebb

Ki vehet részt

  • Healthy Controls (HC)
  • Individuals aged 18-45 years
  • Healthy body weight between 90 and 110 % average body weight since puberty
  • Regular monthly menstrual cycle (if applicable)
  • Edinburgh Handedness Inventory Revised (EHI-R) LQ* score > +200
  • All ethnic backgrounds
  • English is primary language spoken; Anorexia Nervosa (AN)
  • Age 18-45 years old
  • Edinburgh Handedness Inventory Revised (EHI-R) LQ* score > +200
  • All ethnic backgrounds
  • Current diagnosis of anorexia nervosa, including being underweight, will have a severe fear of weight gain, body image distortion and absence of the menstrual cycle over three consecutive months
  • English is primary language spoken; Atypical Anorexia Nervosa (AAN)
  • Age 18-45 years old
  • Edinburgh Handedness Inventory Revised (EHI-R) LQ* score > +200
  • All ethnic backgrounds
  • Meets the criteria for anorexia nervosa except despite significant weight loss, the individual's weight is within or above the normal range
  • English is primary language spoken

Ki nem vehet részt

  • Contraindications to magnetic resonance imaging (MRI) including metal implants or braces (as determined through fMRI screening form); Anorexia Nervosa (AN)
  • Contraindications to MRI including metal implants or braces (as determined through fMRI screening form); Atypical Anorexia Nervosa (AAN)
  • Contraindications to MRI including metal implants or braces (as determined through fMRI screening form)
  • First degree relative with current or past eating disorder
  • Psychiatric Medication use such as selective serotonin reuptake inhibitors (SSRIs), atypical antipsychotics, etc
  • Past or present Axis I psychiatric disorder including substance or alcohol use disorder as determined through structured clinical interview
  • History of significant head trauma
  • Indication of intellectual disability or autism spectrum disorder
  • Major Medical illness that requires medication or have significant impact on subject's life such as: diabetes, Alzheimer's disease or dementia, stroke, learning disability, mobility disorders, cancer, high blood pressure, etc. (to be determined through biological screening form and interview with principal investigator (PI)
  • Recent history of suspected substance abuse or a lifetime history of psychostimulant abuse and/or dependence
  • Lifetime history of bipolar I disorder or psychosis
  • Psychotic illness/other organic brain syndromes, dementia, somatization disorders or conversion disorders
  • Physical conditions (e.g., diabetes mellitus, pregnancy) known to influence eating or weight
  • History of significant head trauma
  • Indication of intellectual disability or autism spectrum disorder
  • Lifetime history of bipolar disorder or psychosis
  • Psychotic illness/other organic brain syndromes, dementia, somatization disorders or conversion disorders
  • Physical conditions (e.g., diabetes mellitus, pregnancy) known to influence eating or weight
  • History of significant head trauma
  • Indication of intellectual disability or autism spectrum disorder
  • Electrolyte, blood count or kidney or liver function abnormalities
  • Electrolyte, blood count or kidney or liver function abnormalities
  • Healthy Controls (HC)
  • Current pregnancy or breast feeding within last 3 months
  • Pregnancy or breast feeding within last 3 months
  • Current substance abuse or dependence in the past 3 months
  • Pregnancy or breast feeding within last 3 months
  • Current substance abuse or dependence in the past 3 months

Helyszínek itt: Egyesült Államok

  • University of California San DiegoSan Diego, Egyesült Államok

A vizsgálatról

Mit akar kideríteni a vizsgálat

Anorexia nervosa (AN) and atypical AN (AAN) are severe psychiatric illnesses associated with high disease burden including high treatment costs and excessive mortality rates. Primary characteristics of AN and AAN are food restriction, associated fear of weight gain, and a disturbance in how one's body weight or shape is experienced.The underlying neural mechanisms for the core illness behaviors of food restriction and body size overestimation in anorexia nervosa and atypical anorexia nervosa are not well understood.

A teljes eredeti leírásKevesebb

This project will use neurofeedback and advanced psychophysical methods to assess and moderate the neural and behavioral responses to stress and relate those results to the naturalistic environment. The results will guide the development of novel interventions.

A vizsgálat csoportja

  • BehavioralA vizsgált kezelés

    Negative Affect Task

    Kezelés: Negative Affect Task

Adatok és források

Regiszteradat
Szerepel a ClinicalTrials.gov-on.
Hivatalos cím
Neural Mechanisms of Negative Affect and Neurofeedback in Anorexia Nervosa
A regiszteradat frissítve
2025. március 30.