Iron Deficiency Anemia (IDA) and the Brain

A regiszter feltételei, szó szerint

Nézd meg, megfelelhetsz-e

Magadról válaszolj. Ez nem döntés: hogy részt vehetsz-e, azt csak a vizsgálat csapata mondhatja meg.

• 16 és 60 év között vagy?IgenNem

Mit akar kideríteni a vizsgálat

This is a trial with an observational and an interventional arm, in patients with moderate to severe anemia and control subjects. The main purposes of this study is to phenotype the scope of neurocognitive deficits from iron deficiency anemia (IDA) in adult women, determine derangements in cerebral perfusion, vascular reactivity, functional connectivity, and blood brain barrier permeability in adult-onset IDA and relate them to neurocognitive deficits, as well as determine the reversibility and durability of both the physiologic and neurocognitive derangements by iron replacement therapy. All eligible subjects will be asked to provide informed consent before participating in the study.

A vizsgálat 3 csoportja

• Intravenous (IV) ironA vizsgált kezelés

  This group will receive intravenous iron (Ferric Derisomaltose) in a single dose of 20 mg/kg (max individual dose of 1000 mg). The drug is administered as an infusion over 30 minutes. 3 months after the infusion, they will receive a 9-month supply of Novaferrum pill to be taken once a day.

  Kezelés: Ferric derisomaltose és NovaFerrum

• Standard of care ironNincs vizsgálati kezelés, összehasonlításként

  This group will be referred to their primary care provider for oral iron therapy. If a participant cannot obtain care from a physician

• Healthy ControlsNincs vizsgálati kezelés, összehasonlításként

  This group will only be participating in the observational part of the study and serve as our controls.