Feasibility of Acquiring Hyperpolarized Imaging in Patients With Meningioma
A legfontosabb adatok
- Hol
- San Francisco (Egyesült Államok)A helyszín megnézése
- Fázis
- 1. fázis
Helyszínek itt: Egyesült Államok
- University of California San FranciscoSan Francisco, Egyesült ÁllamokContact: Wendy MaRésztvevőt keres
Kérdések a vizsgálat csapatának
- Milyen gyakran kell bejárnom, és egy-egy alkalom mennyi ideig tart?
- Megtérítik az utazási költséget?
- Megtarthatom a saját orvosomat?
- Mi történik, ha ki akarok lépni?
Contact the study team: see the registry record → Contacts and Locations
Oldal nyomtatása az orvosomnakA vizsgálat adatai
- Ki végzi
- Charlie Wang, MD, PhD
- Azonosító
- NCT06014905
- A regiszteradat frissítve
- 2026. augusztus 14.
- Eredeti leírás
This is a Pilot/Phase I clinical study of hyperpolarized 13C (HP 13C) pyruvate injection that includes the acquisition of magnetic resonance (MR) data performed on participants with meningioma to evaluate metabolism and aid in the non-invasive characterization of aggressive tumor behaviorA teljes eredeti leírásKevesebb
Pilot/Phase I Study of Feasibility of Acquiring Hyperpolarized Imaging in Patients With Meningioma
This is a Pilot/Phase I clinical study of hyperpolarized 13C (HP 13C) pyruvate injection that includes the acquisition of magnetic resonance (MR) data performed on participants with meningioma to evaluate metabolism and aid in the non-invasive characterization of aggressive tumor behavior
Bevonási feltételek: Known (histopathologically confirmed) or presumed meningioma based on imaging with measurable disease on MRI that shows gadolinium enhancement (at least one cm diameter) intracranially (e.g., not confined to skull base alone); Thirty of the participants plan to have surgical resection within 4 weeks; Participants cannot have contraindication to MRI examinations; Age >=18 years; Have a life expectancy of >12 weeks; Karnofsky Performance Status > 60%; Participants must have adequate renal function (creatinine < 1.5 mg/dL) before imaging. This test must be performed within 60 days prior to hyperpolarized imaging scan; Participants must sign an informed consent indicating that they are aware of the investigational nature of this study; Participants must sign an authorization for the release of their protected health information.
Kizáró feltételek: Uncontrolled blood pressure (Systolic BP≥140 mmHg or diastolic BP ≥>=90 mmHg) despite an optimized regimen of antihypertensive medication; Has any significant medical illnesses that in the investigator's opinion cannot be adequately controlled with appropriate therapy, would compromise the patient's ability to participate in this study or any disease that will obscure toxicity or dangerously impact response to the imaging agent; Has a history of any other cancer (except non-melanoma skin cancer or carcinoma in-situ of the cervix), unless in complete remission and off of all therapy for that disease for a minimum of 3 years; Participants must not be pregnant or breast feeding. Women of childbearing potential are required to obtain a negative pregnancy test within 14 days of Hyperpolarized Imaging scan. Effective contraception (men and women) must be used in participants of child-bearing potential; Participants must be excluded from participating in the study if they are not able to comply with the study and/or follow-up procedures.