Fut, nem toboroz3. fázis
A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis
A legfontosabb adatok
- Ki végzi
- Priovant Therapeutics, Inc.
- Hol
- Ann Arbor, Aurora, Austin, Bakersfield, Baltimore, Bellaire, Beverly Hills, Boston, Carmel, Chicago, Cleveland, Columbus, Dallas, Denver, Detroit, Durham, Erie, Fort Lauderdale, Fullerton, Greenville, Houston, Irvine, Katy, La Jolla, Los Angeles, Madison, Minneapolis, Modesto, Nashville, New York, Oak Park, Omaha, Palisades Park, Philadelphia, Phoenix, Plano, Portland, Prairie Village, Rochester, Round Rock, Sacramento, San Antonio, St Louis, St. Petersburg, Waltham és Winston-Salem (Egyesült Államok)Mind a 46 helyszín megnézéseMég 13 másik országban, 50 helyszínen
- Azonosító
- Állapot
- Fut, nem toboroz
- Fázis
- 3. fázis
- Résztvevők
- 371 fő vett részt
- Kezdés
- 2024. szept. 11.
- Várható befejezés
- 2028. febr. 1.
- A vizsgálat típusa
- Beavatkozással járó, 2 csoportAz egyik csoport placebót (hatóanyag nélküli szert) kap, összehasonlításként.
- A vizsgált kezelések
- Brepocitinib PO QD
- Placebo PO QD
- A regiszteradat frissítve
- 2026. január 12.
Ki vehet részt
- Életkor
- 18 év – 75 év
- Nem
- Nők és férfiak
- Egészséges önkéntesek
- Nem vehetnek részt
A regiszter feltételei, szó szerint
Mind a 11 feltétel megnézéseKevesebb
Ki vehet részt
- Adult subjects (18-75 years old)
- Diagnosis of non-infectious uveitis (intermediate uveitis, posterior uveitis, or panuveitis)
- Active uveitic disease in at least 1 eye
- Weight > 40 kg with a body mass index ≤ 40 kg/m2
Ki nem vehet részt
- cancer within 5 years prior to screening (exceptions for basal cell carcinoma, squamous cell carcinoma, ductal carcinoma in situ of the breast, carcinoma in situ of the uterine cervix, or thyroid carcinoma.)
- Has confirmed or suspected current diagnosis of infectious uveitis History of or have:
- Lymphoproliferative disorder
- active malignancy
- thrombosis or cerebrovascular ischemic event disease within the last 12 months
- active or recent infections
- a high risk for herpes zoster reactivation
Helyszínek itt: Egyesült Államok
Még 13 másik országban, 50 helyszínen
- Ann Arbor, MichiganHospital not named in the registry
- Aurora, ColoradoHospital not named in the registry
- Austin, TexasHospital not named in the registry
- Bakersfield, CaliforniaHospital not named in the registry
- Baltimore, MarylandHospital not named in the registry
- Bellaire, TexasHospital not named in the registry
- Beverly Hills, CaliforniaHospital not named in the registry
- Boston, MassachusettsHospital not named in the registry
- Carmel, IndianaHospital not named in the registry
- Chicago, IllinoisHospital not named in the registry
- Cleveland, OhioHospital not named in the registry
- Columbus, OhioHospital not named in the registry
- Dallas, TexasHospital not named in the registry
- Denver, ColoradoHospital not named in the registry
- Detroit, MichiganHospital not named in the registry
- Durham, North CarolinaHospital not named in the registry
- Erie, PennsylvaniaHospital not named in the registry
- Fort Lauderdale, FloridaHospital not named in the registry
- Fullerton, CaliforniaHospital not named in the registry
- Greenville, South CarolinaHospital not named in the registry
- Houston, TexasHospital not named in the registry
- Irvine, CaliforniaHospital not named in the registry
- Katy, TexasHospital not named in the registry
- La Jolla, CaliforniaHospital not named in the registry
- Los Angeles, CaliforniaHospital not named in the registry
- Madison, WisconsinHospital not named in the registry
- Minneapolis, MinnesotaHospital not named in the registry
- Modesto, CaliforniaHospital not named in the registry
- Nashville, TennesseeHospital not named in the registry
- NYU Langone HealthNew York, Egyesült Államok
- Oak Park, IllinoisHospital not named in the registry
- Omaha, NebraskaHospital not named in the registry
- Palisades Park, New JerseyHospital not named in the registry
- Philadelphia, PennsylvaniaHospital not named in the registry
- Phoenix, ArizonaHospital not named in the registry
- Plano, TexasHospital not named in the registry
- Portland, OregonHospital not named in the registry
- Prairie Village, KansasHospital not named in the registry
- Rochester, MinnesotaHospital not named in the registry
- Round Rock, TexasHospital not named in the registry
- Sacramento, CaliforniaHospital not named in the registry
- San Antonio, TexasHospital not named in the registry
- St Louis, MissouriHospital not named in the registry
- St. Petersburg, FloridaHospital not named in the registry
- Waltham, MassachusettsHospital not named in the registry
- Winston-Salem, North CarolinaHospital not named in the registry
A vizsgálatról
Mit akar kideríteni a vizsgálat
The purpose of this study is to determine the safety and efficacy of brepocitinib in participants with active, non-anterior (intermediate, posterior, or pan) non-infectious uveitis (NIU).
A vizsgálat 2 csoportja
- Arm 1A vizsgált kezelés
Kezelés: Brepocitinib PO QD
- Arm 2Placebo, összehasonlításként
Kezelés: Placebo PO QD
Adatok és források
- Regiszteradat
- Szerepel a ClinicalTrials.gov-on és az EU hivatalos vizsgálati nyilvántartásában (CTIS).
- Hivatalos cím
- A Phase 3 Randomized, Double-Masked, Placebo-Controlled Study to Investigate the Safety and Efficacy of Oral Brepocitinib in Adults With Active, Non-Infectious Intermediate-, Posterior-, and Panuveitis
- A regiszteradat frissítve
- 2026. január 12.